Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2726959 | 0.79 | PDK2 (0.50) | SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL3766395 | 0.79 | CNR2 (0.40) | SMN1; SMN2POLBALDH1A1RAB9AHTT | |
| SCHEMBL3770618 | 0.78 | HPGD (0.49) | SMN1; SMN2MAPTPOLBHSD17B10ALDH1A1 | |
| SCHEMBL14341655 | 0.74 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTPOLBALOX15HSD17B10 | |
| SCHEMBL3766336 | 0.73 | MAPT (0.49) | SMN1; SMN2MAPTALDH1A1RAB9ALMNA | |
| SCHEMBL8953838 | 0.71 | POLB (0.53) | SMN1; SMN2MAPTPOLBALOX15HSD17B10 | |
| SCHEMBL1981807 | 0.70 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTPOLBALOX15HSD17B10 | |
| SCHEMBL3443031 | 0.70 | PTK2 (0.49) | MAPTRAB9ALMNAKMT2AL3MBTL1 | |
| SCHEMBL198522 | 0.69 | FSCN1 (0.55) | SMN1; SMN2MAPTPOLBALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL15788995 | 0.69 | MAOA (0.43) | MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851473-B2 | Amide compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-14 | — | — | US | disclosed |