SCHEMBL3770873

SCHEMBL3770873

CC/C=C/CCCCOc1cccc(NC)c1F

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.37
SLC6A4 P31645 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
PPARG P37231 2/20 0.34
PTPN1 P18031 1/20 0.34
LPAR2 Q9HBW0 3/20 0.33
LPAR3 Q9UBY5 3/20 0.33
LPAR1 Q92633 1/20 0.33
LTB4R Q15722 1/20 0.33
LTB4R2 Q9NPC1 1/20 0.33
KMT2A Q03164 1/20 0.33
HRH1 P35367 1/20 0.32
EPHX2 P34913 3/20 0.32
FAAH O00519 2/20 0.32
CNR1 P21554 2/20 0.32
CACNA1B Q00975 1/20 0.32
CNR2 P34972 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3661806 1.00 L3MBTL1 (0.37) L3MBTL1SLC6A4TDP1PPARGPTPN1
SCHEMBL3771932 0.96 L3MBTL1 (0.38) L3MBTL1SLC6A4TDP1PPARGPTPN1
SCHEMBL3662847 0.96 L3MBTL1 (0.38) L3MBTL1SLC6A4TDP1PPARGPTPN1
SCHEMBL3662881 0.92 EDNRA (0.33) L3MBTL1SLC6A4TDP1PTPN1KMT2A
SCHEMBL3772711 0.92 EDNRA (0.33) L3MBTL1SLC6A4TDP1PTPN1KMT2A
SCHEMBL3664801 0.88 LTB4R (0.36) L3MBTL1SLC6A4TDP1PPARGPTPN1
SCHEMBL3662544 0.88 L3MBTL1 (0.38) L3MBTL1SLC6A4TDP1PPARGPTPN1
SCHEMBL3766276 0.88 LTB4R (0.36) L3MBTL1SLC6A4TDP1PPARGPTPN1
SCHEMBL3766391 0.88 L3MBTL1 (0.38) L3MBTL1SLC6A4TDP1PPARGPTPN1
SCHEMBL3770670 0.86 LTB4R (0.35) L3MBTL1SLC6A4TDP1PPARGPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHIEMCAL COMPANY LIMITED (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME ATL3, NAT1, C5 L3MBTL1 40/4885SLC6A4 3430/4885TDP1 4310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.