SCHEMBL3770937

SCHEMBL3770937

CC(C)c1ccc(-c2ccccc2OCc2ccc(COc3ccccc3-c3ccc(C(C)C)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.54
RXRB P28702 2/20 0.54
RXRG P48443 1/20 0.54
IDO1 P14902 2/20 0.47
SYK P43405 2/20 0.46
PTGER1 P34995 3/20 0.45
PTGER4 P35408 1/20 0.45
PTGER3 P43115 1/20 0.45
PTGER2 P43116 1/20 0.45
MCL1 Q07820 1/20 0.45
AURKB Q96GD4 1/20 0.43
INCENP Q9NQS7 1/20 0.43
MAPT P10636 2/20 0.42
MAPK1 P28482 2/20 0.42
DHODH Q02127 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
USP2 O75604 1/20 0.42
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10785009 0.95 RXRA (0.52) RXRARXRBRXRGIDO1SYK
SCHEMBL3758784 0.89 PTGER1 (0.48) RXRARXRBRXRGSYKPTGER1
SCHEMBL10178454 0.82 RXRA (0.56) RXRARXRBRXRGPTGER1PTGER4
SCHEMBL12603847 0.81 PTGER1 (0.47) RXRARXRBRXRGPTGER1PTGER4
SCHEMBL13738963 0.81 RXRA (0.71) RXRARXRBRXRGIDO1SYK
SCHEMBL13740358 0.81 RXRA (0.75) RXRARXRBRXRGIDO1PTGER1
SCHEMBL8673558 0.81 ADRB2 (0.57) MAPK1TDP1L3MBTL1LMNAKDM4E
SCHEMBL25094104 0.79 PTGER1 (0.59) RXRARXRBRXRGPTGER1PTGER4
SCHEMBL10448531 0.79 RXRA (0.56) RXRARXRBRXRGIDO1PTGER1
SCHEMBL12406129 0.78 PTPRC (0.53) SYKAURKBINCENPMAPTUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8978553-B2 Heat-sensitive lithographic printing plates MITSUBISHI PAPER MILLS LIMITED (JP) 2015-03-17 US disclosed
US-20120192740-A1 FOUNTAIN SOLUTION COMPOSITION FOR LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING METHOD MITSUBISHI PAPER MILLS LIMITED (JP) 2012-08-02 US disclosed
US-20100307359-A1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATES MITSUBISHI PAPER MILLS LIMITED (JP) 2010-12-09 US disclosed