SCHEMBL377249

SCHEMBL377249

O=C(O)Oc1ccc2c3cccc4c(OC(=O)O)ccc(c5cccc1c52)c43

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.40
GAA P10253 4/20 0.40
HSD17B10 Q99714 4/20 0.40
MAPT P10636 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MEN1 O00255 2/20 0.40
ESR1 P03372 2/20 0.40
ESR2 Q92731 2/20 0.40
JAK2 O60674 1/20 0.40
USP2 O75604 1/20 0.40
ALOX15 P16050 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TYMS P04818 3/20 0.39
ALDH1A1 P00352 4/20 0.38
PGR P06401 1/20 0.37
PTGS1 P23219 1/20 0.37
MAPK1 P28482 1/20 0.37
RAB9A P51151 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9649801 0.88 GAA (0.43) KMT2AGAAHSD17B10MAPTSMN1; SMN2
SCHEMBL5246333 0.82 KMT2A (0.50) KMT2AGAAHSD17B10MAPTMEN1
SCHEMBL2638148 0.82 ESR1 (0.48) KMT2AGAAHSD17B10MAPTSMN1; SMN2
SCHEMBL2834876 0.82 ESR1 (0.53) KMT2AGAAHSD17B10MAPTSMN1; SMN2
SCHEMBL2587831 0.81 KDM4E (0.39) KMT2AGAAHSD17B10MAPTMEN1
SCHEMBL6238798 0.81 PKM (0.42) KMT2AGAAHSD17B10MAPTSMN1; SMN2
SCHEMBL10716870 0.81 TYMS (0.43) HSD17B10SMN1; SMN2TYMSALDH1A1TSHR
SCHEMBL297251 0.80 KDM4E (0.31) GAAALDH1A1RAB9ATSHRKDM4E
SCHEMBL9649492 0.79 ESR1 (0.44) KMT2AGAAHSD17B10MAPTSMN1; SMN2
SCHEMBL9350047 0.79 ALDH1A1 (0.48) KMT2AGAAHSD17B10MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2739169-B1 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS MASSACHUSETTS INST TECHNOLOGY (US) 2019-06-12 EP claimed
EP-1687462-B1 METHOD FOR ELECTROCHEMICAL PRODUCTION OF A CRYSTALLINE POROUS METAL ORGANIC SKELETON MATERIAL FRAUNHOFER GES FORSCHUNG (DE) 2019-03-13 EP disclosed
EP-2798013-B1 ANTI-REFLECTIVE COATING LEIBNIZ INST FÜR NEUE MATERIALIEN GEMEINNÜTZIGE GMBH (DE) 2016-08-17 EP disclosed
EP-2168971-B1 Fluid absorption by metal-organic frameworks BASF SE (DE) 2016-08-03 EP disclosed
EP-2230288-B1 METAL-ORGANIC FRAMEWORKS IN REFRIGERATION/HEATING MACHINES BASF SE (DE) 2016-05-25 EP disclosed
EP-2798013-A1 ANTI-REFLECTIVE COATING Leibniz-Institut für Neue Materialien gemeinnützige GmbH (DE) 2014-11-05 EP disclosed
EP-2408536-B1 PROCESS FOR SEPARATING ACID GASES USING AMINE IMPREGNATED METAL ORGANIC FRAMEWORKS BASF SE (DE) 2014-07-30 EP disclosed
EP-2117676-B1 METHOD FOR SEPARATING GASES USING A POROUS METAL ORGANIC FRAMEWORK MATERIAL BASF SE (DE) 2014-06-25 EP disclosed
EP-2408684-B1 BIOLOGICALLY DEGRADABLE MATERIAL BASED ON A POLYMERIC MATERIAL CONTAINING POROUS ORGANOMETALLIC NETWORKS BASF SE (DE) 2013-08-21 EP disclosed
WO-2013098090-A1 ANTI-REFLECTIVE COATING LEIBNIZ-INSTITUT FÜR NEUE MATERIALIEN GEMEINNÜTZIGE GMBH (DE) 2013-07-04 WO disclosed
EP-1687462-A1 METHOD FOR ELECTROCHEMICAL PRODUCTION OF A CRYSTALLINE POROUS METAL ORGANIC SKELETON MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2006-08-09 EP disclosed
WO-2006072573-A2 ADSORPTIVE PRODUCTION OF XENON FROM KRYPTON/XENON GAS MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2006-07-13 WO disclosed
EP-1674555-A1 Concentration of methane in methane containing gas mixtures by adsorption BASF AKTIENGESELLSCHAFT (DE) 2006-06-28 EP disclosed
WO-2005049892-A1 METHOD FOR ELECTROCHEMICAL PRODUCTION OF A CRYSTALLINE POROUS METAL ORGANIC SKELETON MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2005-06-02 WO disclosed
WO-2005049484-A1 METHOD FOR THE CONTROLLED STORAGE AND RELEASE OF GASES USING AN ELECTROCHEMICALLY PRODUCED CRYSTALLINE, POROUS, ORGANOMETALLIC SKELETON MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2005-06-02 WO disclosed
EP-0264543-B1 PERYLENE DERIVATIVES BASF Aktiengesellschaft (DE) 1991-04-03 EP disclosed
EP-0156997-B1 PROCESS FOR THE CONCENTRATION OF LIGHT IN A PLANE SURFACE BASF Aktiengesellschaft (DE) 1988-07-20 EP disclosed
EP-0264543-A2 Perylene derivatives BASF Aktiengesellschaft (DE) 1988-04-27 EP disclosed
EP-0156997-A1 Process for the concentration of light in a plane surface BASF Aktiengesellschaft (DE) 1985-10-09 EP disclosed
EP-0047027-A1 Liquid crystals mixture BBC Aktiengesellschaft Brown, Boveri & Cie. (CH) 1982-03-10 EP disclosed