Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | GAA | P10253 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 1.00 |
| ▸ | PKM | P14618 | 3/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.67 |
| ▸ | JAK2 | O60674 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12941615 | 0.87 | GAA (0.78) | KDM4EGAAMAPTPOLBPKM | |
| SCHEMBL5267565 | 0.86 | KDM4E (0.75) | KDM4EGAAMAPTPOLBPKM | |
| SCHEMBL12941862 | 0.86 | GAA (1.00) | KDM4EGAAMAPTPOLBPKM | |
| SCHEMBL27225457 | 0.81 | ALDH1A1 (1.00) | KDM4EGAAMAPTPOLBPKM | |
| SCHEMBL18222875 | 0.80 | KDM4E (0.67) | KDM4EGAAMAPTPOLBPKM | |
| SCHEMBL7455522 | 0.78 | KDM4E (0.62) | KDM4EGAAMAPTPOLBPKM | |
| SCHEMBL31438664 | 0.77 | ABCG2 (0.68) | KDM4EGAAMAPTPOLBPKM | |
| SCHEMBL5569925 | 0.77 | ABCG2 (0.68) | KDM4EGAAMAPTPOLBPKM | |
| SCHEMBL7455502 | 0.77 | KDM4E (0.61) | KDM4EGAAMAPTPOLBPKM | |
| SCHEMBL27225557 | 0.76 | KDM4E (0.61) | KDM4EGAAMAPTPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7846628-B2 | Hole blocking layer containing photoconductors | XEROX CORPORATION (US) | 2010-12-07 | — | — | US | claimed |
| US-20080311497-A1 | HOLE BLOCKING LAYER CONTAINING PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2008-12-18 | — | — | US | claimed |
| US-7462433-B2 | Undercoat layer containing charge transfer molecule, andTiO2; imaging layer; charge transfer molecule complexes with the TiO2 to form coordination bonds and the coordination bonds provide a reduction in ghosting; electrophotographic imaging members; improved image quality | XEROX CORPORATION (US) | 2008-12-09 | — | — | US | claimed |
| US-20070048639-A1 | Undercoat layer containing charge transfer molecule, andTiO2; imaging layer; charge transfer molecule complexes with the TiO2 to form coordination bonds and the coordination bonds provide a reduction in ghosting; electrophotographic imaging members; improved image quality | XEROX CORPORATION (US) | 2007-03-01 | — | — | US | claimed |
| US-7846628-B2 | Hole blocking layer containing photoconductors | XEROX CORPORATION (US) | 2010-12-07 | — | — | US | disclosed |
| US-20080311497-A1 | HOLE BLOCKING LAYER CONTAINING PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2008-12-18 | — | — | US | disclosed |
| US-7462433-B2 | Undercoat layer containing charge transfer molecule, andTiO2; imaging layer; charge transfer molecule complexes with the TiO2 to form coordination bonds and the coordination bonds provide a reduction in ghosting; electrophotographic imaging members; improved image quality | XEROX CORPORATION (US) | 2008-12-09 | — | — | US | disclosed |
| US-20070048639-A1 | Undercoat layer containing charge transfer molecule, andTiO2; imaging layer; charge transfer molecule complexes with the TiO2 to form coordination bonds and the coordination bonds provide a reduction in ghosting; electrophotographic imaging members; improved image quality | XEROX CORPORATION (US) | 2007-03-01 | — | — | US | disclosed |