Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772637 | 0.77 | KDM4E (1.00) | KDM4EGAAPOLBMAPTPKM | |
| SCHEMBL13791316 | 0.75 | GAA (0.56) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL5267565 | 0.74 | KDM4E (0.75) | KDM4EGAAPOLBMAPTPKM | |
| SCHEMBL7455522 | 0.74 | KDM4E (0.62) | KDM4EGAAPOLBMAPTPKM | |
| SCHEMBL18222875 | 0.72 | KDM4E (0.67) | KDM4EGAAPOLBMAPTPKM | |
| SCHEMBL12941615 | 0.66 | GAA (0.78) | KDM4EGAAPOLBMAPTPKM | |
| SCHEMBL5992503 | 0.65 | KDM4E (0.60) | KDM4EGAAPOLBMAPTPKM | |
| SCHEMBL7941853 | 0.65 | KDM4E (0.69) | KDM4EGAAPOLBMAPTPKM | |
| SCHEMBL12941862 | 0.65 | GAA (1.00) | KDM4EGAAPOLBMAPTPKM | |
| SCHEMBL31619650 | 0.65 | KDM4E (0.59) | KDM4EGAAPOLBMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730152-B1 | Regulating water treatment agent dosage based on operational system stresses | NALCO CHEMICAL CO (US) | 2002-09-18 | — | — | EP | disclosed |