SCHEMBL377310

SCHEMBL377310

O=COP(=O)(O)O.[NaH].[NaH].[NaH]

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.39
BLM P54132 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MPI P34949 1/20 0.31
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27337469 1.00
SCHEMBL875835 1.00
Water SCHEMBL28524171 0.97 FDPS (0.37) FDPSBLMTDP1MPI
SCHEMBL1332890 0.97
SCHEMBL29020521 0.93
SCHEMBL6905808 0.93
Ammonia Solution, Strong SCHEMBL27782827 0.93
SCHEMBL2403749 0.93
SCHEMBL22720208 0.93
Formic Acid SCHEMBL20854282 0.90 FDPS (0.37) FDPSBLMTDP1MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119948053-A Anti-SARS-CoV-2 antigen binding polypeptides, polypeptide complexes, and methods of use thereof 摩德斯医疗股份有限公司 2025-05-06 CN claimed
EP-3808743-B1 HIV REPLICATION INHIBITING PYRIMIDINES JANSSEN PHARMACEUTICA NV (BE) 2022-07-20 EP claimed
EP-3808743-A1 HIV REPLICATION INHIBITING PYRIMIDINES Janssen Pharmaceutica NV (BE) 2021-04-21 EP claimed
EP-3230455-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) INFECTIONS Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2017-10-18 EP claimed
WO-2016092041-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) INFECTIONS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2016-06-16 WO claimed
US-7037917-B2 HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICA, N.V. (BE) 2006-05-02 US claimed
US-20040039005-A1 Nitrogen compounds such as 4-((4-amino-5-bromo-6-(4-cyano-2,6-dimethylphenyloxy)-2 -pyrimidinyl)amino)benzonitrile, used as protease inhibitors for prophylaxis of viral diseases JANSSEN PHARMACEUTICA N.V. (BE) 2004-02-26 US claimed
US-20030199473-A1 Substituted diamino-1,3,5-triazine derivatives JANSSEN PHARMACEUTICA N.V. 2003-10-23 US claimed
EP-3528791-B1 DISPERSIBLE COMPOSITIONS JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) 2023-12-06 EP disclosed
EP-4248947-A2 DISPERSIBLE COMPOSITIONS Janssen Sciences Ireland Unlimited Company (IE) 2023-09-27 EP disclosed
EP-1663240-B2 COMBINATIONS OF A PYRIMIDINE CONTAINING NNRTI WITH RT INHIBITORS JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) 2023-03-01 EP disclosed
EP-3808743-B1 HIV REPLICATION INHIBITING PYRIMIDINES JANSSEN PHARMACEUTICA NV (BE) 2022-07-20 EP disclosed
EP-1632232-B3 Salt of 4[[4-[[4-(2-Cyanoethenyl)-2,6-dimethylphenyl]amino]-2-Pyrimidinyl]amino]benzonitrile JANSSEN PHARMACEUTICA NV (BE) 2022-03-30 EP disclosed
US-20220008417-A1 COMBINATIONS OF A PYRIMIDINE CONTAINING NNRTI WITH RT INHIBITORS Janssen Sciences Ireland Unlimited Company (IE) 2022-01-13 US disclosed
WO-1999050250-A1 HIV INHIBITING PYRIMIDINE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 1999-10-07 WO disclosed
EP-0945442-A1 Trisubstituted pyrimidine derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1999-09-29 EP disclosed
EP-0945443-A1 HIV inhibiting pyrimidine derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1999-09-29 EP disclosed
EP-0945447-A1 Trisubstituted 1,3,5-triazine derivatives for treatment of HIV infections JANSSEN PHARMACEUTICA N.V. (BE) 1999-09-29 EP disclosed
WO-1999045025-A1 ACYLATED BETULIN AND DIHYDROBETULIN DERIVATIVES, PREPARATION THEREOF AND USE THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1999-09-10 WO disclosed
EP-0834507-A1 Substituted diamino-1,3,5-triazine derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1998-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199473-A1 Substituted diamino-1,3,5-triazine derivatives CCR1, CCR6, CCR5 FDPS 2146/4885BLM 4118/4885TDP1 2017/4885
US-20040039005-A1 Nitrogen compounds such as 4-((4-amino-5-bromo-6-(4-cyano-2,6-dimethylphenyloxy)-2 -pyrimidinyl)amino)benzonitrile, used as protease inhibitors for prophylaxis of viral diseases CPN1, CTRL, HPN FDPS 4184/4885BLM 1342/4885TDP1 828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.