SCHEMBL377331

SCHEMBL377331

c1ccc(OPOc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.50
TSHR P16473 1/20 0.50
CA4 P22748 1/20 0.45
KCNA3 P22001 1/20 0.41
CA5A P35218 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
NR1H2 P55055 1/20 0.38
BAX Q07812 1/20 0.38
MAOA P21397 1/20 0.38
KCNH2 Q12809 1/20 0.37
KDM4E B2RXH2 1/20 0.37
GLA P06280 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
TAAR1 Q96RJ0 1/20 0.36
ALDH1A1 P00352 1/20 0.36
RECQL P46063 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL11160688 1.00 LTA4H (0.50) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL30805666 0.97 LTA4H (0.47) LTA4HTSHRCA4KCNA3CA5A
Hydrochloric Acid SCHEMBL28827565 0.97 LTA4H (0.47) LTA4HTSHRCA4KCNA3CA5A
Hydrochloric Acid SCHEMBL2155162 0.97 LTA4H (0.47) LTA4HTSHRCA4KCNA3CA5A
Ethylene Glycol SCHEMBL28694519 0.87 ALDH1A1 (0.50) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL28484853 0.84 LTA4H (0.38) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL11582580 0.83 CA4 (0.50) LTA4HTSHRCA4KCNA3CA5A
Hydrochloric Acid SCHEMBL25266154 0.81 CA4 (0.48) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL11428561 0.81 ALDH1A1 (0.40) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL18406143 0.79 CYP3A4 (0.46) LTA4HTSHRCA4CA5ACA5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371575-A Purification method of sodium gluconate 广东东阳光药业股份有限公司 2025-01-28 CN claimed
CN-118389189-A Coke-preventing decoking agent for boiler and preparation method thereof 北京联发迈通科技有限公司 2024-07-26 CN claimed
CN-117924363-A Room-temperature phosphorescent material, preparation method and room-temperature phosphorescent light-cured ink 西北工业大学 2024-04-26 CN claimed
CN-117866014-A Quinoline C-4 phosphoryl derivative and preparation method and application thereof 西北师范大学 2024-04-12 CN claimed
CN-117794896-A Protease inhibitors for the treatment of coronavirus infections 斯克里普斯研究学院 2024-03-29 CN claimed
CN-117417461-A Modified cellulose, solar cell interconnection layer thereof and solar cell 福建农林大学 2024-01-19 CN claimed
CN-116815496-A Dustproof and corrosion-resistant fabric and preparation method thereof 吴江市兴业纺织有限公司 2023-09-29 CN claimed
CN-114507255-B Difunctional polymerizable low-migration photoinitiator and preparation method and application thereof 华南理工大学 2023-08-22 CN claimed
CN-113461545-B Organic phosphorescence composition, preparation method and application thereof 季华恒烨(佛山)电子材料有限公司 2023-07-18 CN claimed
CN-116120205-A Preparation method of butanone azine 中国天辰工程有限公司 2023-05-16 CN claimed
US-20100099875-A1 NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS PHOSPHOENIX SARL (FR) 2010-04-22 US claimed
EP-1899358-A2 NOVEL P-CHIRAL FUNCTIONALISED ARYLPHOSPHINES AND DERIVATIVES, THE PREPARATION AND USE THEREOF FOR ASYMMETRICAL CATALYSIS Phosphoenix SARL (FR) 2008-03-19 EP claimed
WO-2006136695-A2 NOVEL P-CHIRAL FUNCTIONALISED ARYLPHOSPHINES AND DERIVATIVES, THE PREPARATION AND USE THEREOF FOR ASYMMETRICAL CATALYSIS PHOSPHOENIX SARL (FR) 2006-12-28 WO claimed
EP-0903372-B1 Synergistic polyamide stabilization method CLARIANT FINANCE BVI LTD (VG) 2004-12-01 EP claimed
US-6063843-A MOLDED ARTICLES, FIBERS; PHOTOSTABILITY, HEAT AND OXIDATION RESISTANCE CLARIANT FINANCE (BVI) LIMITED (VG) 2000-05-16 US claimed
US-5969014-A UNIFORMLY INCORPORATING STEARICALLY HINDERED PHENYL PHOSPHONITE AND NONHYDROXYL SUBSTITUTED OXANILIDE; EXTRUDED ARTICLES, FIBERS EXHIBITING OUTSTANDING COLOR BRIGHTNESS AND COLOR STABILITY CLARIANT FINANCE (BVI) LIMITED (VG) 1999-10-19 US claimed
EP-0903372-A1 Synergistic polyamide stabilization method Clariant Finance (BVI) Limited (VG) 1999-03-24 EP claimed
US-4241208-A STABILIZERS OF SYNTHETIC POLYMERS AGAINST HEAT AND LIGHT SANKYO COMPANY LIMITED (JP) 1980-12-23 US claimed
US-4126632-A OF ACRYLONITRILE TO 1,4-DICYANOBUTENES IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-11-21 US claimed
US-4066615-A PHOTOSTABILITY, THERMAL STABILITY SANKYO COMPANY LIMITED (JA) 1978-01-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099875-A1 NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS PNP, NANP, PHOSPHO1 LTA4H 2800/4885TSHR 3165/4885CA4 1378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.