SCHEMBL377344

SCHEMBL377344

C=C(C(=O)O)C(=O)NCCC

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP3 P08254 1/20 0.40
MMP9 P14780 1/20 0.40
KDM4C Q9H3R0 1/20 0.39
EPHX1 P07099 2/20 0.39
MCL1 Q07820 1/20 0.38
KDM4E B2RXH2 4/20 0.37
TDP1 Q9NUW8 1/20 0.37
PLA2G2A P14555 2/20 0.36
NPC1 O15118 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALOX15 P16050 1/20 0.35
PLA2G4A P47712 1/20 0.35
ALDH1A1 P00352 2/20 0.35
PAOX Q6QHF9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28977204 0.87 EPHX1 (0.47) MMP2EPHX1KDM4EPLA2G2ANPC1
SCHEMBL18754166 0.82 MMP1 (0.40) MMP1MMP2MMP3MMP9KDM4C
SCHEMBL2935709 0.81
SCHEMBL583601 0.80
SCHEMBL6858080 0.77 MMP1 (0.52) MMP1MMP2MMP3MMP9KDM4C
SCHEMBL149370 0.76
Dimethylamine SCHEMBL9702906 0.76 MMP1 (0.43) MMP1MMP2MMP3MMP9KDM4C
SCHEMBL3279311 0.76
SCHEMBL24359054 0.74
SCHEMBL16410518 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8758954-B2 Process for preparing membranes FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2014-06-24 US disclosed
EP-2473260-A1 PROCESS FOR PREPARING COMPOSITE MEMBRANES Fujifilm Manufacturing Europe BV (NL) 2012-07-11 EP disclosed
US-20120165420-A1 Process for Preparing Composite Membranes FUJIFILM MANUFACTURING EUROPE B.V (NL) 2012-06-28 US disclosed
US-20120024697-A1 Membranes FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2012-02-02 US disclosed
EP-2408544-A1 MEMBRANES Fujifilm Manufacturing Europe BV (NL) 2012-01-25 EP disclosed
EP-2408542-A1 PROCESS FOR PREPARING COMPOSITE MEMBRANES Fujifilm Manufacturing Europe B.V. (NL) 2012-01-25 EP disclosed
US-20120006685-A1 Process for Preparing Composite Membranes FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2012-01-12 US disclosed
US-20110097645-A1 Process for Preparing Membranes FUJIFILM MANUFACTURING EUROPE B.V (NL) 2011-04-28 US disclosed
EP-2303955-A1 PROCESS FOR PREPARING MEMBRANES Fujifilm Manufacturing Europe BV (NL) 2011-04-06 EP disclosed
WO-2011027138-A1 PROCESS FOR PREPARING COMPOSITE MEMBRANES FUJIFILM MANUFACTURING EUROPE BV (NL) 2011-03-10 WO disclosed
WO-2010106357-A1 PROCESS FOR PREPARING COMPOSITE MEMBRANES FUJIFILM MANUFACTURING EUROPE BV (NL) 2010-09-23 WO disclosed
WO-2010106356-A1 MEMBRANES FUJIFILM MANUFACTURING EUROPE BV (NL) 2010-09-23 WO disclosed
WO-2010082069-A1 PROCESS FOR PREPARING MEMBRANES FUJIFILM MANUFACTURING EUROPE BV (NL) 2010-07-22 WO disclosed
WO-2010007399-A1 PROCESS FOR PREPARING MEMBRANES FUJIFILM MANUFACTURING EUROPE BV (NL) 2010-01-21 WO disclosed