Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940482 | 0.91 | MMP1 (0.46) | MMP1MMP2MMP3MMP9EPHX1 | |
| SCHEMBL6850994 | 0.89 | NPC1 (0.47) | MMP1MMP2MMP3MMP9EPHX1 | |
| SCHEMBL9866601 | 0.87 | CTSD (0.48) | MMP1MMP2MMP3MMP9EPHX1 | |
| SCHEMBL3414867 | 0.85 | — | — | |
| SCHEMBL6583643 | 0.85 | — | — | |
| SCHEMBL583601 | 0.85 | — | — | |
| SCHEMBL18808374 | 0.84 | EPHX1 (0.50) | MMP1MMP2MMP3MMP9EPHX1 | |
| SCHEMBL28553543 | 0.84 | MMP1 (0.41) | MMP1MMP2MMP3MMP9EPHX1 | |
| SCHEMBL25766357 | 0.83 | MMP1 (0.44) | MMP1MMP2MMP3MMP9EPHX1 | |
| SCHEMBL8395945 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9034798-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CAPROTEC BIOANALYTICS GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| WO-2015031725-A1 | TRANSITION METAL-CATALYZED IMIDATION OF ARENES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-03-05 | — | — | WO | disclosed |
| WO-2009032843-A2 | DEUTERATED ETHAMBUTOLS AND THEIR USE | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-03-12 | — | — | WO | disclosed |
| US-7169544-B2 | Thermally developable materials containing thermal solvents | EASTMAN KODAK COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| US-7169544-B2 | Thermally developable materials containing thermal solvents | EASTMAN KODAK COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| US-6737193-B2 | ACTIVE MATERIALS IN THE POSITIVE ELECTRODES OF BATTERIES. NOVEL METHODS FOR PREPARING THE TETRAKETOPIPERAZINE UNIT-CONTAINING COMPOUNDS INCLUDE: (I) REACTING AN OXALYL HALIDE AND AN OXAMIDE, AND ADDING WATER OR AN AQUEOUS ALKALI | IM&T RESEARCH, INC. | 2004-05-18 | — | — | US | disclosed |
| US-20030148188-A1 | Active materials in the positive electrodes of batteries. Novel methods for preparing the tetraketopiperazine unit-containing compounds include: (i) reacting an oxalyl halide and an oxamide, and adding water or an aqueous alkali | IM&T RESEARCH, INC. | 2003-08-07 | — | — | US | disclosed |
| US-4782005-A | N,N'-diorgano dicarboxamides as oxygen inhibitors in radiation sensitive acrylate compositions | POLYCHROME CORP. (US) | 1988-11-01 | — | — | US | disclosed |