Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15608731 | 0.99 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL31722609 | 0.90 | MEN1 (0.52) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| Hydrochloric Acid SCHEMBL7581386 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL3779074 | 0.87 | MEN1 (0.57) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL16049759 | 0.86 | HTT (0.57) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL16126099 | 0.86 | HTT (0.57) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL15774906 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| Hydrochloric Acid SCHEMBL15774920 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL14188141 | 0.84 | HTT (0.55) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL978529 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140088080-A1 | IMIDAZOPYRIDINE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2014-03-27 | — | — | US | disclosed |
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088080-A1 | IMIDAZOPYRIDINE COMPOUNDS | GUCY1A1, PDE2A, GUCY1A2 | SMN1; SMN2 1311/4885NPC1 3106/4885RAB9A 916/4885 |
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | TOP2A, TOP1, TOP2B | SMN1; SMN2 4553/4885NPC1 3959/4885RAB9A 2665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.