Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15774906 | 0.91 | SMN1; SMN2 (0.59) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| Hydrochloric Acid SCHEMBL15774920 | 0.90 | SMN1; SMN2 (0.57) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL1709810 | 0.88 | MEN1 (0.58) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL29266964 | 0.88 | MEN1 (0.58) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL3774077 | 0.87 | SMN1; SMN2 (0.56) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL31722609 | 0.87 | MEN1 (0.52) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| Hydrochloric Acid SCHEMBL15608731 | 0.86 | SMN1; SMN2 (0.55) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| Hydrochloric Acid SCHEMBL7581386 | 0.86 | SMN1; SMN2 (0.51) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL31722389 | 0.85 | MEN1 (0.56) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL10565066 | 0.84 | MEN1 (0.57) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447090-B2 | Imidazopyridine compounds | ASTELLAS PHARMA INC. (JP) | 2016-09-20 | — | — | US | disclosed |
| EP-2716642-B1 | IMIDAZOPYRIDINE COMPOUND | ASTELLAS PHARMA INC (JP) | 2016-07-20 | — | — | EP | disclosed |
| US-20140088080-A1 | IMIDAZOPYRIDINE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2014-03-27 | — | — | US | disclosed |
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088080-A1 | IMIDAZOPYRIDINE COMPOUNDS | GUCY1A1, PDE2A, GUCY1A2 | MEN1 3450/4885KMT2A 2785/4885NPSR1 3703/4885 |
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | TOP2A, TOP1, TOP2B | MEN1 4010/4885KMT2A 2291/4885NPSR1 4722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.