SCHEMBL3774288

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3773424	0.94	KMT2A (0.61)	KMT2AOPRK1NPC1RAB9AUSP2
	SCHEMBL3774347	0.90	SLC6A5 (0.55)	KMT2AHRH3MEN1TSHRDRD2
	SCHEMBL3765381	0.90	KMT2A (0.46)	KMT2ANPC1RAB9AUSP2HRH3
	SCHEMBL3774004	0.89	DRD2 (0.51)	KMT2AHRH3MEN1POLBHPGD
	SCHEMBL3779258	0.89	KMT2A (0.51)	KMT2ANPC1RAB9AHRH3MEN1
	SCHEMBL3767807	0.89	DRD2 (0.56)	KMT2AHRH3MEN1DRD2DRD4
	SCHEMBL3769105	0.89	KMT2A (0.51)	KMT2AHRH3MEN1LMNADRD2
	SCHEMBL3776073	0.89	KMT2A (0.70)	KMT2AHRH3MEN1ALDH1A1TSHR
	SCHEMBL3771229	0.88	KMT2A (0.50)	KMT2AOPRK1HRH3ALDH1A1TSHR
	SCHEMBL3762917	0.88	USP2 (0.52)	KMT2AOPRK1NPC1RAB9AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.