Sugi Predict

Sugi Predict / Compounds / SCHEMBL3774341

SCHEMBL3774341

SCHEMBL3774341

O=C(C1CCNCC1)C1CCNCC1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.65
▸ GABRA1 P14867 2/20 0.65
▸ GABRG2 P18507 2/20 0.65
▸ GABRB3 P28472 2/20 0.65
▸ GABRA5 P31644 2/20 0.65
▸ GABRA3 P34903 2/20 0.65
▸ GABRA2 P47869 2/20 0.65
▸ GABRA6 Q16445 2/20 0.65
▸ GABRP O00591 1/20 0.65
▸ GABRD O14764 1/20 0.65
▸ GABRB1 P18505 1/20 0.65
▸ GABRB2 P47870 1/20 0.65
▸ GABRA4 P48169 1/20 0.65
▸ GABRE P78334 1/20 0.65
▸ PMP22 Q01453 1/20 0.65
▸ GABRG1 Q8N1C3 1/20 0.65
▸ GABRG3 Q99928 1/20 0.65
▸ GABRQ Q9UN88 1/20 0.65
▸ CHRNB2 P17787 3/20 0.48
▸ CHRNA3 P32297 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27508984 0.97 TSHR (0.62) TSHRGABRA1GABRG2GABRB3GABRA5
Hydrochloric Acid SCHEMBL27430608 0.97 TSHR (0.62) TSHRGABRA1GABRG2GABRB3GABRA5
SCHEMBL1484884 0.97 TSHR (0.62) TSHRGABRA1GABRG2GABRB3GABRA5
Bromide SCHEMBL27312283 0.97 TSHR (0.62) TSHRGABRA1GABRG2GABRB3GABRA5
Hydrochloric Acid SCHEMBL28132000 0.94 TSHR (0.59) TSHRGABRA1GABRG2GABRB3GABRA5
SCHEMBL11126760 0.92 TSHR (0.56) TSHRGABRA1GABRG2GABRB3GABRA5
SCHEMBL9253898 0.89 TSHR (0.54) TSHRGABRA1GABRG2GABRB3GABRA5
SCHEMBL3709913 0.89 TSHR (0.54) TSHRGABRA1GABRG2GABRB3GABRA5
Piperazine SCHEMBL28251749 0.88 CHRNB2 (0.54) TSHRGABRA1GABRG2GABRB3GABRA5
SCHEMBL12862907 0.87 TSHR (0.52) TSHRGABRA1GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109923108-A Pyridyl-substituted indole compounds 百时美施贵宝公司 2019-06-21 — — CN claimed
CN-109715617-A Dimethoxyphenyl-substituted indole compounds as inhibitors of TLR7, TLR8 or TLR9 百时美施贵宝公司 2019-05-03 — — CN claimed
CN-108727338-A A kind of 4- piperidines ketone compounds and the preparation method and application thereof 福建医科大学 2018-11-02 — — CN claimed
CN-108191742-A Bis- aryl methylene -4- piperidines ketone compounds of 3,5- of 4- P-acetamido benzene sulfonyls base substitution and preparation method thereof 滨州医学院 2018-06-22 — — CN claimed
CN-107910576-A The preparation method of the anionic polymer film of a kind of high chemical stability 武汉大学 2018-04-13 — — CN claimed
CN-105778896-B Phenyl（4 piperidyls）The small-molecule fluorescent probe of ketone class hERG potassium-channels 山东大学 2018-01-12 — — CN claimed
CN-103717589-B For treating or prevent the compound of respiratory syncytial virus disease 弗·哈夫曼-拉罗切有限公司 2016-08-17 — — CN claimed
CN-105778896-A Small molecular fluorescent probe of phenyl(4-piperidyl) ketone hERG potassium channel 山东大学 2016-07-20 — — CN claimed
EP-4506344-A1 1,4-DIHETEROCYCLIC SUBSTITUTED AROMATIC RING OR AROMATIC HETEROCYCLIC COMPOUND AND USE THEREOF Bebetter Med Inc. (CN) 2025-02-12 — — EP disclosed
US-20250034116-A1 1,4-DIHETEROCYCLIC SUBSTITUTED AROMATIC RING OR AROMATIC HETEROCYCLIC COMPOUND AND USE THEREOF BEBETTER MED INC. (CN) 2025-01-30 — — US disclosed
CN-114478545-B Pyrene imide compound, preparation method thereof, cathode interface material and semiconductor device 兰州大学 2023-08-01 — — CN disclosed
CN-110520127-A Piperidinyl-substituted and piperazinyl-substituted heteroaromatic carboxamides as modulators of GPR6 TAKEDA PHARMACEUTICALS CO 2019-11-29 — — CN disclosed
CN-110478495-A Target conjugate and its particle and preparation TARVEDA THERAPEUTICS INC 2019-11-22 — — CN disclosed
CN-110177553-A Alkyl Pyrrolopyrimidine is like object and its preparation and application 北卡罗来纳大学教堂山分校 2019-08-27 — — CN disclosed
CN-1033586-C Imidazo [2, 1-b ] [3] benzazepine derivatives and their use as anti-inflammatory agents JANSSEN PHARMACEUTICA NV (BE) 1996-12-18 — — CN disclosed
CN-1023895-C Process for producing N-aralkyl piperidinemethanol derivatives MERRELL DOW PHARMA (US) 1994-03-02 — — CN disclosed
CN-1022566-C Process for preparing novel substituted 1-piperidinoalkylene-pyridopyrimidones or thiazolopyrimidinones JANSSEN PHARMACEUTICA NV (BE) 1993-10-27 — — CN disclosed
CN-1068118-A Imidazo [2, 1-b ] [3] benzazepine derivatives, compositions and methods of use JANSSEN PHARMACEUTICA NV (BE) 1993-01-20 — — CN disclosed
CN-86104408-A Process for producing N-aralkyl piperidinemethanol derivatives — 1987-05-20 — — CN disclosed
US-4246268-A ANTIPSYCHOTICS, TRANQUILIZERS, NEUROLEPTICS COMPOUNDS AND NOVEL INTERMEDIATES RICHARDSON-MERRELL INC. (US) 1981-01-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034116-A1 1,4-DIHETEROCYCLIC SUBSTITUTED AROMATIC RING OR AROMATIC HETEROCYCLIC COMPOUND AND USE THEREOF CYP46A1, CYP4A22, CYP2C19 TSHR 2943/4885GABRA1 518/4885GABRG2 938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.