Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2083152 | 0.90 | ALDH1A1 (0.50) | ALDH1A1MAPK1HTTHIF1ACYP3A4 | |
| SCHEMBL2082959 | 0.90 | ALDH1A1 (0.50) | ALDH1A1MAPK1HTTHIF1ACYP3A4 | |
| SCHEMBL16095369 | 0.78 | ERN1 (0.39) | ALDH1A1MAPK1HTTHIF1ACYP3A4 | |
| SCHEMBL7408717 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPK1HTTHIF1ACYP3A4 | |
| SCHEMBL31073706 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPK1HTTHIF1ACYP3A4 | |
| SCHEMBL1762953 | 0.78 | TDP1 (0.41) | ALDH1A1MAPK1HTTHIF1ACYP3A4 | |
| SCHEMBL21596680 | 0.73 | TDP1 (0.44) | ALDH1A1MAPK1HTTHIF1ACYP3A4 | |
| SCHEMBL2404855 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPK1HTTCYP3A4MEN1 | |
| SCHEMBL16992887 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPK1HTTHIF1ATDP1 | |
| SCHEMBL202290 | 0.73 | ERN1 (0.41) | ALDH1A1HTTCYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324283-A1 | PROCESS FOR PRODUCING LAUROLACTAM | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2010-12-23 | — | — | US | disclosed |