Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3774501 | 0.90 | ALDH1A1 (0.43) | ALDH1A1MAPK1HIF1AHTTAHR | |
| SCHEMBL21596680 | 0.82 | TDP1 (0.44) | ALDH1A1MAPK1HIF1AHTTTDP1 | |
| SCHEMBL30612243 | 0.82 | TDP1 (0.44) | ALDH1A1MAPK1HIF1AHTTTDP1 | |
| SCHEMBL16992887 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPK1HIF1AHTTTDP1 | |
| SCHEMBL30625727 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPK1HIF1AHTTTDP1 | |
| SCHEMBL8078061 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPK1HIF1AHTTAHR | |
| SCHEMBL7408717 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPK1HIF1AHTTMEN1 | |
| SCHEMBL2711056 | 0.78 | TSHR (0.41) | ALDH1A1MAPK1HIF1AAHRTDP1 | |
| SCHEMBL16095369 | 0.78 | ERN1 (0.39) | ALDH1A1MAPK1HIF1AHTTTDP1 | |
| SCHEMBL1720997 | 0.78 | TDP1 (0.37) | ALDH1A1MAPK1HIF1AHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443458-A | Aminocrotonyl 3,5-dinitropyridine useful as adjuncts to radiation therapy | MERCK & CO., INC. (US) | 1984-04-17 | — | — | US | claimed |
| EP-2738161-B1 | METHOD FOR PRODUCING AMIDE COMPOUND | UBE INDUSTRIES (JP) | 2018-04-11 | — | — | EP | disclosed |
| EP-2738162-B1 | METHOD FOR PRODUCING AMIDE COMPOUND | UBE INDUSTRIES (JP) | 2018-01-03 | — | — | EP | disclosed |
| EP-2548862-B1 | METHOD FOR PRODUCING AMIDE COMPOUND | UBE INDUSTRIES (JP) | 2016-06-08 | — | — | EP | disclosed |
| CN-105315213-A | Method for producing amide compound | UBE INDUSTRIES | 2016-02-10 | — | — | CN | disclosed |
| US-9242931-B2 | Method for producing amide compound | UBE INDUSTRIES, LTD. (JP) | 2016-01-26 | — | — | US | disclosed |
| CN-102892752-B | Process for producing amide compound | UBE INDUSTRIES | 2015-03-25 | — | — | CN | disclosed |
| US-8962826-B2 | Method for producing amide compound | UBE INDUSTRIES, LTD. (JP) | 2015-02-24 | — | — | US | disclosed |
| US-8816069-B2 | Method for producing amide compound | UBE INDUSTRIES, LTD. (JP) | 2014-08-26 | — | — | US | disclosed |
| CN-103864657-A | METHOD FOR PRODUCING AMIDE COMPOUND | UBE INDUSTRIES | 2014-06-18 | — | — | CN | disclosed |
| EP-2548862-A1 | METHOD FOR PRODUCING AMIDE COMPOUND | Ube Industries, Ltd. (JP) | 2013-01-23 | — | — | EP | disclosed |
| US-20130005960-A1 | METHOD FOR PRODUCING AMIDE COMPOUND | UBE INDUSTRIES, LTD. (JP) | 2013-01-03 | — | — | US | disclosed |
| US-8309714-B2 | Process for producing laurolactam | UBE INDUSTRIES, LTD. (JP) | 2012-11-13 | — | — | US | disclosed |
| US-8163899-B2 | Process for producing laurolactam | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20100267944-A1 | PROCESS FOR PRODUCING LAUROLACTAM | UBE INDUSTRIES, LTD. (JP) | 2010-10-21 | — | — | US | disclosed |
| EP-2223911-A1 | METHOD FOR PRODUCTION OF LAUROLACTAM | Ube Industries, Ltd. (JP) | 2010-09-01 | — | — | EP | disclosed |
| EP-2123635-A1 | METHOD FOR PRODUCTION OF LAUROLACTAM | National University Corporation Nagoya University (JP) | 2009-11-25 | — | — | EP | disclosed |
| US-5378244-A | Bright blue; colorfastness; hair dyes | KAO CORPORATION (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0559217-A1 | 2-Alkoxy-3,5-diaminopyridine derivatives and their salts, and dye compositions for keratinous fibers containing them | KAO CORPORATION (JP) | 1993-09-08 | — | — | EP | disclosed |
| US-4443458-A | Aminocrotonyl 3,5-dinitropyridine useful as adjuncts to radiation therapy | MERCK & CO., INC. (US) | 1984-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005960-A1 | METHOD FOR PRODUCING AMIDE COMPOUND | ADH1C, ADH5, ALKBH3 | ALDH1A1 57/4885MAPK1 3683/4885HIF1A 2707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.