SCHEMBL377492

SCHEMBL377492

C=C(CCC(=O)O)C(N)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.50
EGLN1 Q9GZT9 3/20 0.50
ALKBH5 Q6P6C2 1/20 0.50
SUCNR1 Q9BXA5 1/20 0.50
GABRR1 P24046 2/20 0.42
KDM4E B2RXH2 2/20 0.40
KDM5C P41229 2/20 0.40
PHF8 Q9UPP1 2/20 0.40
KDM2A Q9Y2K7 2/20 0.40
SLC15A2 Q16348 1/20 0.39
MAPK1 P28482 1/20 0.39
SLC13A3 Q8WWT9 1/20 0.39
OR51E2 Q9H255 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.38
TSHR P16473 2/20 0.38
CYP1A2 P05177 2/20 0.38
GABRR3 A8MPY1 1/20 0.38
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38
HDAC3 O15379 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2990567 0.91 EGLN1 (0.41) LMNAEGLN1ALKBH5SUCNR1GABRR1
SCHEMBL167050 0.88 TDP1 (0.44) LMNAKDM4EMAPK1OR51E2TSHR
SCHEMBL1555935 0.84 SLC22A6 (0.55) LMNAEGLN1ALKBH5SUCNR1GABRR1
SCHEMBL31190090 0.84 LMNA (0.55) LMNAGABRR1SLC22A6TSHRCYP1A2
Succinic Acid SCHEMBL28326414 0.84 LMNA (0.45) LMNAEGLN1ALKBH5SUCNR1GABRR1
SCHEMBL2143362 0.82 TSHR (0.57) LMNAOR51E2SLC22A6TSHRTHRB
SCHEMBL4155714 0.82 TSHR (0.57) LMNAOR51E2SLC22A6TSHRTHRB
Succinic Acid SCHEMBL18604000 0.82 LMNA (0.75) LMNAEGLN1ALKBH5SUCNR1GABRR1
SCHEMBL6921772 0.80 LMNA (0.41) LMNAEGLN1ALKBH5SUCNR1GABRR1
SCHEMBL11608326 0.80 TDP1 (0.38) LMNAKDM4EOR51E2CYP1A2BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220403127-A1 MIXED-CHARGE COPOLYMER ANTIBIOFILM COATINGS NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2022-12-22 US claimed
US-20190119415-A1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2019-04-25 US claimed
US-9873786-B2 Synthetic composition and coating for cell culture CORNING INCORPORATED (US) 2018-01-23 US claimed
EP-2310104-B1 MIXED GRAFT POLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2017-10-18 EP claimed
EP-2152405-B2 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2017-04-05 EP claimed
EP-2705142-B1 SYNTHETIC COMPOSITION AND COATING FOR CELL CULTURE. CORNING INC (US) 2016-08-10 EP claimed
US-9115238-B2 Swellable synthetic microcarriers for culturing cells CORNING INCORPORATED (US) 2015-08-25 US claimed
US-8673988-B2 Graft copolymers for ion exchange chromatography MERCK PATENT GMBH (DE) 2014-03-18 US claimed
EP-2705142-A1 SYNTHETIC COMPOSITION AND COATING FOR CELL CULTURE. Corning Incorporated (US) 2014-03-12 EP claimed
US-8426176-B2 Synthetic microcarriers for culturing cells CORNING INCORPORATED (US) 2013-04-23 US claimed
JP-2011529508-A 2011-12-08 JP claimed
US-20110136925-A1 GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-06-09 US claimed
EP-2310104-A1 GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY Merck Patent GmbH (DE) 2011-04-20 EP claimed
US-20100317113-A1 SYNTHETIC MICROCARRIERS FOR CULTURING CELLS CORNING INCORPORATED 2010-12-16 US claimed
US-20100304482-A1 SWELLABLE SYNTHETIC MICROCARRIERS FOR CULTURING CELLS CORNING INCORPORATED 2010-12-02 US claimed
WO-2010138702-A1 SWELLABLE SYNTHETIC MICROCARRIERS FOR CULTURING CELLS CORNING INCORPORATED (US) 2010-12-02 WO claimed
WO-2010138687-A1 SYNTHETIC MICROCARRIERS FOR CULTURING CELLS CORNING INCORPORATED (US) 2010-12-02 WO claimed
EP-2153877-A1 Mixed graft polymers for ion exchange chromatography MERCK PATENT GmbH (DE) 2010-02-17 EP claimed
WO-2010012358-A1 GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2010-02-04 WO claimed
EP-0476117-A1 THERMOREVERSIBLE HEAT-THICKENING POLYACRYLAMIDES. EASTMAN KODAK CO (US) 1992-03-25 EP claimed