Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | KDM5C | P41229 | 4/20 | 0.39 |
| ▸ | KDM6B | O15054 | 2/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377492 | 0.91 | LMNA (0.50) | EGLN1LMNAALKBH5SUCNR1PHF8 | |
| SCHEMBL370643 | 0.88 | — | — | |
| SCHEMBL167050 | 0.80 | TDP1 (0.44) | LMNAALOX15HSD17B10KDM4ELDHA | |
| SCHEMBL1555935 | 0.76 | SLC22A6 (0.55) | EGLN1LMNAALKBH5SUCNR1ALOX15 | |
| SCHEMBL31190090 | 0.76 | LMNA (0.55) | LMNAALOX15HSD17B10GABRR1FOLH1 | |
| Itaconate SCHEMBL25434060 | 0.76 | ALOX15 (0.60) | EGLN1LMNAALKBH5SUCNR1ALOX15 | |
| Succinic Acid SCHEMBL28326414 | 0.76 | LMNA (0.45) | EGLN1LMNAALKBH5SUCNR1PHF8 | |
| Itaconate SCHEMBL28511688 | 0.75 | ALOX15 (0.65) | LMNAALOX15HSD17B10KDM4ELDHA | |
| Itaconate SCHEMBL16880252 | 0.75 | ALOX15 (0.65) | EGLN1LMNAALKBH5SUCNR1ALOX15 | |
| SCHEMBL4155714 | 0.74 | TSHR (0.57) | LMNAALOX15HSD17B10OR51E2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190119415-A1 | GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2019-04-25 | — | — | US | claimed |
| US-20140183136-A1 | GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2014-07-03 | — | — | US | claimed |
| EP-2152405-B1 | GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2012-10-17 | — | — | EP | claimed |
| US-20100181254-A1 | GRAFT COPOLYMER FOR CATION- EXCHANGE CHROMATOGRAPHY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-07-22 | — | — | US | claimed |