SCHEMBL3775314

SCHEMBL3775314

COC(=O)OC[C@H]1O[C@@](O)(Oc2nn(C(C)C)c(C)c2Cc2ccc(OC(C)C)cc2)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC5A1 P13866 12/20 0.65
SLC5A2 P31639 12/20 0.65
GAA P10253 1/20 0.33
P2RX3 P56373 2/20 0.32
POLB P06746 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
LMNA P02545 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3782741 0.94 SLC5A1 (0.73) SLC5A1SLC5A2GAAP2RX3POLB
SCHEMBL3767779 0.91 SLC5A2 (0.54) SLC5A1SLC5A2
SCHEMBL3769351 0.89 SLC5A1 (0.51) SLC5A1SLC5A2KDM4E
SCHEMBL3767395 0.88 SLC5A1 (0.51) SLC5A1SLC5A2P2RX3
SCHEMBL3779163 0.86 SLC5A2 (0.60) SLC5A1SLC5A2
SCHEMBL3769872 0.86 SLC5A2 (0.48) SLC5A1SLC5A2LMNA
SCHEMBL3778945 0.85 SLC5A1 (0.47) SLC5A1SLC5A2
SCHEMBL3771611 0.85 SLC5A2 (0.47) SLC5A1SLC5A2P2RX3
SCHEMBL2253384 0.84 SLC5A2 (0.89) SLC5A1SLC5A2
SCHEMBL3764892 0.83 SLC5A1 (0.45) SLC5A1SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070072813-A1 Methods for preventing and treating metabolic disorders and new pyrazole-O-glycoside derivatives AJINOMOTO CO., INC. (JP) 2007-03-29 US claimed
US-20100317575-A1 PHARMACEUTICAL COMPOSITION COMPRISING A PYRAZOLE-O-GLUCOSIDE DERIVATIVE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-12-16 US disclosed
US-20070072813-A1 Methods for preventing and treating metabolic disorders and new pyrazole-O-glycoside derivatives AJINOMOTO CO., INC. (JP) 2007-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070072813-A1 Methods for preventing and treating metabolic disorders and new pyrazole-O-glycoside derivatives IAPP, G6PC1, GPR119 SLC5A1 4/4885SLC5A2 6/4885GAA 202/4885
US-20100317575-A1 PHARMACEUTICAL COMPOSITION COMPRISING A PYRAZOLE-O-GLUCOSIDE DERIVATIVE SLC5A1, SLC5A2, G6PC1 SLC5A1 1/4885SLC5A2 2/4885GAA 102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.