Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 3/20 | 0.40 |
| ▸ | CASP9 | P55211 | 3/20 | 0.40 |
| ▸ | CYCS | P99999 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3702676 | 0.94 | DRD3 (0.37) | APAF1CASP3CASP9CYCSDRD3 | |
| SCHEMBL3691829 | 0.91 | HPGD (0.39) | DRD3DRD2DRD4PIM1CYP3A4 | |
| SCHEMBL3696495 | 0.88 | APAF1 (0.41) | APAF1CASP3CASP9CYCSMAPT | |
| SCHEMBL3693009 | 0.86 | DRD3 (0.42) | DRD3DRD2DRD4TNFMAPT | |
| SCHEMBL3701627 | 0.85 | APAF1 (0.43) | APAF1CASP3CASP9CYCSMAPT | |
| SCHEMBL3698794 | 0.83 | SMN1; SMN2 (0.42) | DRD3DRD2DRD4TNFCYP3A4 | |
| SCHEMBL3704317 | 0.83 | MAPT (0.40) | APAF1CASP3CASP9CYCSMAPT | |
| SCHEMBL3699379 | 0.83 | HTR2A (0.41) | DRD3DRD2MAPTRAB9AKMT2A | |
| SCHEMBL3704147 | 0.82 | APAF1 (0.52) | APAF1CASP3CASP9CYCSCYP3A4 | |
| SCHEMBL3703745 | 0.82 | HTR2A (0.42) | DRD3DRD2MAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040701-B2 | Apaf-1 inhibitor compounds | LABORATORIOS SALVAT, S.A. (ES) | 2015-05-26 | — | — | US | disclosed |
| EP-2460798-A2 | APAF-1 INHIBITOR COMPOUNDS | Laboratorios SALVAT, S.A. (ES) | 2012-06-06 | — | — | EP | disclosed |
| US-20120122868-A1 | APAF-1 INHIBITOR COMPOUNDS | LABORATORIOS SALVAT, S.A. (ES) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122868-A1 | APAF-1 INHIBITOR COMPOUNDS | APAF1, API5, AIFM1 | APAF1 1/4885CASP3 13/4885CASP9 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.