Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 14/20 | 0.46 |
| ▸ | PGR | P06401 | 12/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3775634 | 1.00 | NR3C1 (0.46) | NR3C1NR3C2PGRTSHRBLM | |
| SCHEMBL3774628 | 0.83 | NR3C1 (0.59) | NR3C1NR3C2PGR | |
| SCHEMBL3774626 | 0.83 | NR3C1 (0.59) | NR3C1NR3C2PGR | |
| SCHEMBL3676726 | 0.77 | NR3C1 (0.45) | NR3C1NR3C2PGR | |
| SCHEMBL3676729 | 0.77 | NR3C1 (0.45) | NR3C1NR3C2PGR | |
| SCHEMBL3224912 | 0.76 | NR3C1 (0.53) | NR3C1NR3C2PGRTSHRBLM | |
| SCHEMBL3794702 | 0.69 | TSHR (0.44) | NR3C1NR3C2PGRTSHR | |
| SCHEMBL4437162 | 0.66 | NR3C1 (0.53) | NR3C1NR3C2PGR | |
| SCHEMBL4434916 | 0.66 | NR3C1 (0.53) | NR3C1NR3C2PGR | |
| SCHEMBL3224128 | 0.64 | NR3C1 (0.49) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317863-A1 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions and Uses Thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-16 | — | — | US | claimed |
| US-20100317863-A1 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions and Uses Thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317863-A1 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions and Uses Thereof | NR3C1, MC2R, NR3C2 | NR3C1 1/4885NR3C2 3/4885PGR 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.