Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13256322 | 0.84 | IDO1 (0.61) | IDO1CYP1A2CYP2D6MAPTNPSR1 | |
| SCHEMBL8599963 | 0.81 | CYP1A2 (0.59) | CYP1A2CYP2D6MAPTLMNAALDH1A1 | |
| SCHEMBL8598555 | 0.79 | CYP1A2 (0.60) | CYP1A2CYP2D6MAPTNPSR1LMNA | |
| Bromide SCHEMBL4917871 | 0.79 | IDO1 (0.54) | IDO1CYP1A2CYP2D6MAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL10967775 | 0.79 | IDO1 (0.56) | IDO1CYP1A2CYP2D6MAPTNPSR1 | |
| SCHEMBL1708732 | 0.78 | IDO1 (1.00) | IDO1CYP1A2MAPTNPSR1LMNA | |
| SCHEMBL3690757 | 0.77 | CYP1A2 (0.53) | IDO1CYP1A2CYP2D6MAPTNPSR1 | |
| SCHEMBL1742521 | 0.76 | CYP1A2 (0.57) | CYP1A2CYP2D6MAPTNPSR1ALDH1A1 | |
| SCHEMBL27543660 | 0.76 | CYP1A2 (0.57) | CYP1A2CYP2D6MAPTNPSR1LMNA | |
| SCHEMBL12727872 | 0.76 | CYP1A2 (0.57) | CYP1A2MAPTNPSR1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075177-A2 | ANTIBIOTICS TARGETING MREB | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2007-07-05 | — | — | WO | claimed |
| US-20060241185-A1 | Antibiotics targeting MreB | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2006-10-26 | — | — | US | claimed |
| US-7855228-B2 | Antibiotics targeting MreB | THE BOARD OF TRUSTEES OF THE LELAND STAMFORD JUNIOR UNIVERSITY (US) | 2010-12-21 | — | — | US | disclosed |
| WO-2007075177-A2 | ANTIBIOTICS TARGETING MREB | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2007-07-05 | — | — | WO | disclosed |
| US-20060241185-A1 | Antibiotics targeting MreB | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241185-A1 | Antibiotics targeting MreB | SMC4, INCENP, DDB1 | IDO1 2985/4885CYP1A2 2380/4885CYP2D6 1350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.