Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3770900 | 0.92 | ALDH1A1 (0.45) | ALDH1A1TSHRDNM1TDP1CA12 | |
| SCHEMBL3770386 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRDNM1KCNH2HRH4 | |
| SCHEMBL3771930 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRDNM1HRH4HRH3 | |
| SCHEMBL706918 | 0.80 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL28506154 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRDNM1HRH4HRH3 | |
| SCHEMBL3768534 | 0.77 | — | — | |
| SCHEMBL8158855 | 0.76 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL8166184 | 0.76 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL8166662 | 0.76 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL8169552 | 0.76 | ALDH1A1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809464-B2 | Polymers functionalized with halosilanes containing an amino group | BRIDGESTONE CORPORATION (JP) | 2014-08-19 | — | — | US | claimed |
| US-20120309906-A1 | POLYMERS FUNCTIONALIZED WITH HALOSILANES CONTAINING AN AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2012-12-06 | — | — | US | claimed |
| US-8258332-B2 | Polymers functionalized with halosilanes containing an amino group | BRIDGESTONE CORPORATION (JP) | 2012-09-04 | — | — | US | claimed |
| US-20100317818-A1 | POLYMERS FUNCTIONALIZED WITH HALOSILANES CONTAINING AN AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2010-12-16 | — | — | US | claimed |
| US-8809464-B2 | Polymers functionalized with halosilanes containing an amino group | BRIDGESTONE CORPORATION (JP) | 2014-08-19 | — | — | US | disclosed |
| US-20120309906-A1 | POLYMERS FUNCTIONALIZED WITH HALOSILANES CONTAINING AN AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2012-12-06 | — | — | US | disclosed |
| US-8258332-B2 | Polymers functionalized with halosilanes containing an amino group | BRIDGESTONE CORPORATION (JP) | 2012-09-04 | — | — | US | disclosed |
| US-20100317818-A1 | POLYMERS FUNCTIONALIZED WITH HALOSILANES CONTAINING AN AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317818-A1 | POLYMERS FUNCTIONALIZED WITH HALOSILANES CONTAINING AN AMINO GROUP | MSN, PARG, ALG1 | ALDH1A1 3885/4885TSHR 2843/4885DNM1 3164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.