Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.68 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.68 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.68 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.68 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | TSPO | P30536 | 1/20 | 0.68 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.68 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.62 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.51 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.51 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.51 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19005913 | 0.87 | S1PR1 (0.52) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL3772519 | 0.87 | LPAR3 (0.51) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL13030815 | 0.83 | S1PR4 (0.75) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL5500454 | 0.83 | S1PR4 (0.75) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| Phosphoric Acid SCHEMBL6665386 | 0.82 | MAPT (0.54) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL18993886 | 0.82 | S1PR4 (0.73) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL17482409 | 0.81 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL3885 | 0.81 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL20798182 | 0.81 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL22910837 | 0.81 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190183910-A1 | ENHANCING DNA REPAIR AND PREVENTING AGING AND ITS CONSEQUENCES IN REPRODUCTIVE AND OTHER CELLS | OKTAY, KUTLUK (US) | 2019-06-20 | — | — | US | claimed |
| WO-2017223152-A1 | ENHANCING DNA REPAIR AND PREVENTING AGING AND ITS CONSEQUENCES IN REPRODUCTIVE AND OTHER CELLS | NEW YORK MEDICAL COLLEGE (US) | 2017-12-28 | — | — | WO | claimed |
| US-5663404-A | ANTITUMOR AGENTS; ANTIINFLAMMATORY AGENTS | ONCOMEMBRANE (US) | 1997-09-02 | — | — | US | claimed |
| EP-0671917-A4 | METHOD FOR INHIBITION OF CELL MOTILITY BY SPHINGOSINE-1-PHOSPHATE, ITS DERIVATIVES AND MIMETICS AND METHOD OF SYNTHESIZING SPHINGOSINE-1-PHOSPHATE AND ITS DERIVATIVES. | BIOMEMBRANE INST (US) | 1997-06-18 | — | — | EP | claimed |
| EP-0671917-A1 | METHOD FOR INHIBITION OF CELL MOTILITY BY SPHINGOSINE-1-PHOSPHATE, ITS DERIVATIVES AND MIMETICS AND METHOD OF SYNTHESIZING SPHINGOSINE-1-PHOSPHATE AND ITS DERIVATIVES | ONCOMEMBRANE, INC. (US) | 1995-09-20 | — | — | EP | claimed |
| US-5391800-A | Protecting hydroxyl groups of sphingosine, deprotecting C1, phosphorylating, deprotecting C3; free of L-threo isomer | THE BIOMEMBRANE INSTITUTE (US) | 1995-02-21 | — | — | US | claimed |
| US-5260288-A | Administering an inflammation inhibitory amount | THE BIOMEMBRANE INSTITUTE (US) | 1993-11-09 | — | — | US | claimed |
| WO-1993019760-A1 | METHOD FOR INHIBITION OF CELL MOTILITY BY SPHINGOSINE-1-PHOSPHATE, ITS DERIVATIVES AND MIMETICS AND METHOD OF SYNTHESIZING SPHINGOSINE-1-PHOSPHATE AND ITS DERIVATIVES | THE BIOMEMBRANE INSTITUTE (US) | 1993-10-14 | — | — | WO | claimed |
| US-20230152317-A1 | DIAGNOSIS AND TREATMENT OF COVID-19 | LONDON HEALTH SCIENCES CENTRE RESEARCH INC. (CA) | 2023-05-18 | — | — | US | disclosed |
| WO-2021207858-A1 | DIAGNOSIS AND TREATMENT OF COVID-19 | LONDON HEALTH SCIENCES CENTRE RESEARCH INC. (CA) | 2021-10-21 | — | — | WO | disclosed |
| EP-2962698-B1 | PHARMACEUTICAL COMPOSITION INCLUDING MIGRATORY FACTOR FOR GUIDING PLURIPOTENT STEM CELLS TO INJURY | LIFE SCIENCE INST INC (JP) | 2021-05-12 | — | — | EP | disclosed |
| US-10369162-B2 | Pharmaceutical composition including migratory factor for guiding pluripotent stem cells to damage | CLIO, INC. (JP) | 2019-08-06 | — | — | US | disclosed |
| US-20190183910-A1 | ENHANCING DNA REPAIR AND PREVENTING AGING AND ITS CONSEQUENCES IN REPRODUCTIVE AND OTHER CELLS | OKTAY, KUTLUK (US) | 2019-06-20 | — | — | US | disclosed |
| US-10034889-B2 | Pharmaceutical composition including migratory factor for guiding pluripotent stem cells to damage | CLIO, INC. (JP) | 2018-07-31 | — | — | US | disclosed |
| US-5663404-A | ANTITUMOR AGENTS; ANTIINFLAMMATORY AGENTS | ONCOMEMBRANE (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0671917-A4 | METHOD FOR INHIBITION OF CELL MOTILITY BY SPHINGOSINE-1-PHOSPHATE, ITS DERIVATIVES AND MIMETICS AND METHOD OF SYNTHESIZING SPHINGOSINE-1-PHOSPHATE AND ITS DERIVATIVES. | BIOMEMBRANE INST (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0671917-A1 | METHOD FOR INHIBITION OF CELL MOTILITY BY SPHINGOSINE-1-PHOSPHATE, ITS DERIVATIVES AND MIMETICS AND METHOD OF SYNTHESIZING SPHINGOSINE-1-PHOSPHATE AND ITS DERIVATIVES | ONCOMEMBRANE, INC. (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5391800-A | Protecting hydroxyl groups of sphingosine, deprotecting C1, phosphorylating, deprotecting C3; free of L-threo isomer | THE BIOMEMBRANE INSTITUTE (US) | 1995-02-21 | — | — | US | disclosed |
| US-5260288-A | Administering an inflammation inhibitory amount | THE BIOMEMBRANE INSTITUTE (US) | 1993-11-09 | — | — | US | disclosed |
| WO-1993019760-A1 | METHOD FOR INHIBITION OF CELL MOTILITY BY SPHINGOSINE-1-PHOSPHATE, ITS DERIVATIVES AND MIMETICS AND METHOD OF SYNTHESIZING SPHINGOSINE-1-PHOSPHATE AND ITS DERIVATIVES | THE BIOMEMBRANE INSTITUTE (US) | 1993-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10369162-B2 | Pharmaceutical composition including migratory factor for guiding pluripotent stem cells to damage | S1PR1, S1PR3, S1PR4 | S1PR1 1/4885S1PR4 3/4885S1PR3 2/4885 |
| US-10034889-B2 | Pharmaceutical composition including migratory factor for guiding pluripotent stem cells to damage | S1PR1, S1PR3, S1PR4 | S1PR1 1/4885S1PR4 3/4885S1PR3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.