Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.52 |
| ▸ | TSPO | P30536 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GMNN | O75496 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3777505 | 0.87 | S1PR1 (0.68) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL3772519 | 0.82 | LPAR3 (0.51) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL2854224 | 0.78 | S1PR1 (0.46) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| Phosphoric Acid SCHEMBL6665386 | 0.78 | MAPT (0.54) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL1512942 | 0.75 | SPHK2 (0.61) | ALDH1A1MEN1KMT2ATP53MAPT | |
| SCHEMBL22986833 | 0.75 | SPHK2 (0.61) | ALDH1A1MEN1KMT2ATP53MAPT | |
| SCHEMBL15235841 | 0.75 | SPHK2 (0.61) | ALDH1A1MEN1KMT2ATP53MAPT | |
| Iodide SCHEMBL5689882 | 0.74 | SPHK2 (0.59) | ALDH1A1MEN1KMT2ATP53MAPT | |
| SCHEMBL15941659 | 0.74 | PLA2G4A (0.60) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL15948851 | 0.74 | PLA2G4A (0.60) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174812-A1 | CROSSLINKED POLYMERS PREPARED FROM FUNCTIONAL MONOMERS HAVING IMIDAZOLIUM, PYRIDINIUM, ARYL-SUBSTITUTED UREA OR ARYL-SUBSTITUTED THIOUREA GROUPS AND USES THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2017-06-22 | — | — | US | disclosed |