Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.46 |
| ▸ | CACNG8 | Q8WXS5 | 3/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3110872 | 0.98 | CHEK1 (0.55) | CHEK1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29734052 | 0.98 | CHEK1 (0.55) | CHEK1GRIN2DGRIN3BGRIN1GRIN2A | |
| Potassium SCHEMBL3642930 | 0.96 | CHEK1 (0.54) | CHEK1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6009055 | 0.76 | ERCC5 (0.53) | CHEK1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31619545 | 0.76 | ERCC5 (0.53) | CHEK1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5879190 | 0.76 | CHEK1 (0.58) | CHEK1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3125353 | 0.74 | PARP1 (0.49) | CHEK1PARP1KDM4ECA12CA9 | |
| SCHEMBL8144559 | 0.74 | IMPDH2 (0.50) | CHEK1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6645136 | 0.74 | KDM4E (0.48) | CHEK1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3106487 | 0.74 | FEN1 (0.50) | CHEK1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317607-A1 | USE OF COMPOUNDS FOR PREPARING ANTI-TUBERCULOSIS AGENTS | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317607-A1 | USE OF COMPOUNDS FOR PREPARING ANTI-TUBERCULOSIS AGENTS | TPX2, DCXR, RRM2 | CHEK1 3090/4885GRIN2D 4202/4885GRIN3B 3968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.