SCHEMBL3778293

SCHEMBL3778293

O=C1OCC2CCC12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31084649 1.00
SCHEMBL23409268 1.00
SCHEMBL23342828 0.91 KDM4E (0.32)
SCHEMBL23417055 0.89
SCHEMBL7909083 0.85
SCHEMBL20715180 0.85 ALDH1A1 (0.32)
SCHEMBL56213 0.85
SCHEMBL16116751 0.85 ALDH1A1 (0.32)
SCHEMBL8444553 0.85 ALDH1A1 (0.32)
SCHEMBL6383420 0.85 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0349204-A2 Use and regeneration of reagents using coupled reactions and permselective barriers BEND RESEARCH, INC. (US) 1990-01-03 EP claimed
CN-114787139-B Methods and intermediates for preparing MCL1 inhibitors 吉利德科学公司 2025-03-11 CN disclosed
US-10759899-B2 Recyclable polymers based on ring-fused gamma-butyrolactones COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2020-09-01 US disclosed
US-20190040191-A1 RECYCLABLE POLYMERS BASED ON RING-FUSED GAMMA-BUTYROLACTONES NATIONAL SCIENCE FOUNDATION 2019-02-07 US disclosed
US-20100324305-A1 PRODUCTION METHOD OF POLYCYCLIC LACTAMS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-23 US disclosed
US-20090118519-A1 Production Method of Polycyclic Lactams SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-07 US disclosed
EP-2014647-A1 PROCESS FOR PRODUCING POLYCYCLIC LACTAM Sumitomo Chemical Company, Limited (JP) 2009-01-14 EP disclosed
US-5502075-A Leukotriene-B4 derivatives, process for their production and their use as pharmaceutical agents SCHERING AKTIENGESELLSCHAFT (DE) 1996-03-26 US disclosed