Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1638343 | 0.89 | CTSK (0.43) | CA12CA1CA14CA7CTSK | |
| SCHEMBL4653239 | 0.87 | DGKA (0.43) | CA12CA1CA14CA7CTSK | |
| SCHEMBL20503257 | 0.86 | DGKA (0.46) | ALDH1A1CTSKTDP1 | |
| SCHEMBL8002118 | 0.86 | DGKA (0.46) | ALDH1A1CTSKTDP1 | |
| SCHEMBL31088250 | 0.86 | DGKA (0.46) | ALDH1A1CTSKTDP1 | |
| SCHEMBL25438156 | 0.86 | DGKA (0.46) | ALDH1A1CTSKTDP1 | |
| SCHEMBL30516551 | 0.86 | DGKA (0.46) | ALDH1A1CTSKTDP1 | |
| SCHEMBL18985138 | 0.85 | TDP1 (0.44) | CA12CA1CA14CA7CTSK | |
| SCHEMBL1949382 | 0.84 | CA12 (0.40) | CA12CA1CA14CA7CTSK | |
| SCHEMBL28363958 | 0.81 | TSHR (0.54) | ALDH1A1CA12CA1CA14CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367111-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2024-05-15 | — | — | EP | disclosed |
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |
| CN-110770224-B | Indole derivatives as efflux pump inhibitors | 罗格斯新泽西州立大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-110143961-B | Pyrrolo-pyridone bifunctional molecular compound based on VHL ligand-induced BET degradation | 江苏省中医药研究院 | 2022-03-29 | — | — | CN | disclosed |
| CN-113825748-A | Antimicrobial compounds and methods | 库扎环球有限责任公司 | 2021-12-21 | — | — | CN | disclosed |
| EP-3828172-A1 | DUAL MECHANISM INHIBITORS FOR THE TREATMENT OF DISEASE | Aerie Pharmaceuticals, Inc. (US) | 2021-06-02 | — | — | EP | disclosed |
| EP-3354643-B1 | DUAL MECHANISM INHIBITORS FOR THE TREATMENT OF DISEASE | AERIE PHARMACEUTICALS INC (US) | 2020-10-28 | — | — | EP | disclosed |
| CN-110770224-A | Indole derivatives as efflux pump inhibitors | 罗格斯新泽西州立大学 | 2020-02-07 | — | — | CN | disclosed |
| CN-110337429-A | Ionizable cation lipid for RNA delivery | 阿克丘勒斯治疗公司 | 2019-10-15 | — | — | CN | disclosed |
| CN-107105661-A | Big ring picolinamide compound with Fungicidally active | 美国陶氏益农公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-107105662-A | Big ring picolinamide as fungicide purposes | 美国陶氏益农公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-106928252-A | A kind of compound of suppression ROCK and preparation method and application | 成都先导药物开发有限公司 | 2017-07-07 | — | — | CN | disclosed |
| CN-104768952-B | PI3K inhibitors | 山东亨利医药科技有限责任公司 | 2016-10-19 | — | — | CN | disclosed |
| CN-104334559-A | Novel beta-lactamase inhibitor and process for preparing the same | MEIJI SEIKA PHARMA CO LTD | 2015-02-04 | — | — | CN | disclosed |
| EP-2408759-A1 | PROCESSES FOR PREPARING AMINO-SUBSTITUTED GAMMA-LACTAMS | Valorisation-Recherche, Société en Commandite (CA) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010105367-A1 | PROCESSES FOR PREPARING AMINO-SUBSTITUTED GAMMA-LACTAMS | VALORISATION-RECHERCHE SOCIETE EN COMMANDITE (CA) | 2010-09-23 | — | — | WO | disclosed |
| CN-101821263-A | Dipeptoid prodrugs and the use thereof | BAYER HEALTHCARE AG | 2010-09-01 | — | — | CN | disclosed |
| CN-101675059-A | Macrocyclic compounds | CHUGAI PHARMACEUTICAL CO LTD | 2010-03-17 | — | — | CN | disclosed |
| CN-1033584-C | Benzo-fused lactams that promote release of growth hormone | MERCK & CO INC (US) | 1996-12-18 | — | — | CN | disclosed |