SCHEMBL3778452

SCHEMBL3778452

COc1ccc(NC(=O)N2CCN(c3nc(-c4ccccc4)ns3)CC2)cn1

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 17/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3771081 0.86 FAAH (1.00) FAAH
SCHEMBL3772331 0.85 FAAH (0.78) FAAH
SCHEMBL3766108 0.85 FAAH (0.75) FAAH
SCHEMBL3763276 0.85 FAAH (0.71) FAAH
SCHEMBL4471079 0.84 FAAH (0.81) FAAH
SCHEMBL3765682 0.84 FAAH (0.70) FAAH
SCHEMBL3766297 0.84 FAAH (1.00) FAAH
SCHEMBL3767907 0.84 FAAH (0.72) FAAH
SCHEMBL3768195 0.84 FAAH (0.77) FAAH
SCHEMBL4466434 0.84 FAAH (0.91) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7851473-B2 Amide compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-12-14 US disclosed
US-20080312226-A1 Amide Compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-12-18 US disclosed
EP-1813606-A1 AMIDE COMPOUND Takeda Pharmaceutical Company Limited (JP) 2007-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312226-A1 Amide Compound FAAH, FAAH2, CNR2 FAAH 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.