Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 18/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3776531 | 0.91 | MAP4K4 (0.37) | MAP4K4PDE5AKCNH2MINK1 | |
| SCHEMBL3780099 | 0.90 | MAP4K4 (0.36) | MAP4K4PDE5AKCNH2MINK1 | |
| SCHEMBL3771894 | 0.87 | LTB4R (0.35) | — | |
| SCHEMBL3781381 | 0.86 | FFAR4 (0.38) | — | |
| SCHEMBL3779162 | 0.85 | FFAR4 (0.37) | MAP4K4 | |
| SCHEMBL3775790 | 0.85 | CHRNB1 (0.40) | MAP4K4PDE5AKCNH2MINK1 | |
| SCHEMBL3782750 | 0.85 | FFAR4 (0.40) | — | |
| SCHEMBL3771875 | 0.84 | FFAR4 (0.38) | — | |
| SCHEMBL3777917 | 0.83 | FFAR4 (0.35) | — | |
| SCHEMBL3772521 | 0.82 | ABL1 (0.38) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317698-A1 | Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxyalkylene-Cyclopropanamine Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them | LES LABORATOIRES SERVIER (FR) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317698-A1 | Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxyalkylene-Cyclopropanamine Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them | CHRNA6, CHRNE, CHRNG | MALT1 1484/4885MAP4K4 3835/4885PDE5A 1837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.