Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.52 |
| ▸ | TST | Q16762 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3771807 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL3769984 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL3771212 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL3783878 | 0.99 | ALDH1A1 (0.53) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL2791873 | 0.90 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL2791869 | 0.90 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL13013520 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL3782310 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL13013522 | 0.86 | MAPT (0.44) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL13013509 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KDM4EPOLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100322880-A1 | UVA FILTERS BASED ON ASCORBIC ACID DERIVATIVES | MERCK PATENT GMBH | 2010-12-23 | — | — | US | disclosed |
| US-20100322880-A1 | UVA FILTERS BASED ON ASCORBIC ACID DERIVATIVES | MERCK PATENT GMBH | 2010-12-23 | — | — | US | disclosed |
| US-20100322880-A1 | UVA FILTERS BASED ON ASCORBIC ACID DERIVATIVES | MERCK PATENT GMBH | 2010-12-23 | — | — | US | disclosed |
| WO-2009097951-A1 | UVA FILTER BASED ON ASCORBIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100322880-A1 | UVA FILTERS BASED ON ASCORBIC ACID DERIVATIVES | C1R, VDR, C1S | ALDH1A1 80/4885KDM4E 3422/4885POLB 2018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.