Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.59 |
| ▸ | CES1 | P23141 | 8/20 | 0.59 |
| ▸ | CES2 | O00748 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | PPARD | Q03181 | 5/20 | 0.50 |
| ▸ | PPARA | Q07869 | 5/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3777756 | 1.00 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL3787603 | 1.00 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL9435633 | 1.00 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL3777162 | 1.00 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL8501029 | 0.92 | FAAH (0.52) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL4803939 | 0.92 | FAAH (0.52) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL30312764 | 0.90 | FAAH (0.50) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL626978 | 0.90 | FAAH (0.50) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL8015947 | 0.89 | CES1 (0.52) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL8015133 | 0.89 | CES1 (0.52) | FAAHCES1CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160151282-A1 | AMPHOTERIC LIPOSOME FORMULATIONS | MARINA BIOTECH INC (US) | 2016-06-02 | — | — | US | disclosed |
| US-9283186-B2 | Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | MARINA BIOTECH, INC. (US) | 2016-03-15 | — | — | US | disclosed |
| US-20140178462-A1 | AMPHOTERIC LIPOSOMES COMPRISING NEUTRAL LIPIDS | MARINA BIOTECH, INC. (US) | 2014-06-26 | — | — | US | disclosed |
| EP-2462924-A2 | Improvements in or relating to amphoteric liposomes. | Marina Biotech, Inc. (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20120135065-A1 | Amphoteric Liposomes, A Method Of Formulating An Amphoteric Liposome And A Method Of Loading An Amphoteric Liposome | MARINA BIOTECH, INC. | 2012-05-31 | — | — | US | disclosed |
| US-20100330154-A1 | AMPHOTERIC LIPOSOMES COMPRISING NEUTRAL LIPIDS | MARINA BIOTECH, INC. | 2010-12-30 | — | — | US | disclosed |
| US-20080088046-A1 | Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | NOVOSOM AG (DE) | 2008-04-17 | — | — | US | disclosed |
| US-20080089932-A1 | Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | MARINA BIOTECH, INC. | 2008-04-17 | — | — | US | disclosed |
| EP-1911443-A1 | Amphoteric liposomes, method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | Novosom AG (DE) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135065-A1 | Amphoteric Liposomes, A Method Of Formulating An Amphoteric Liposome And A Method Of Loading An Amphoteric Liposome | LIPA, SGMS1, SGMS2 | FAAH 248/4885CES1 894/4885CES2 2491/4885 |
| US-20100330154-A1 | AMPHOTERIC LIPOSOMES COMPRISING NEUTRAL LIPIDS | LIPA, CETP, SGMS1 | FAAH 1830/4885CES1 544/4885CES2 2494/4885 |
| US-20160151282-A1 | AMPHOTERIC LIPOSOME FORMULATIONS | LIPA, SGMS1, SGMS2 | FAAH 241/4885CES1 867/4885CES2 3272/4885 |
| US-20140178462-A1 | AMPHOTERIC LIPOSOMES COMPRISING NEUTRAL LIPIDS | LIPA, CETP, SGMS1 | FAAH 1830/4885CES1 544/4885CES2 2494/4885 |
| US-20080089932-A1 | Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | LIPA, SGMS1, SGMS2 | FAAH 248/4885CES1 894/4885CES2 2491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.