Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 7/20 | 0.76 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.76 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.76 |
| ▸ | MGLL | Q99685 | 1/20 | 0.76 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.61 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.61 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.54 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29669939 | 0.91 | NR5A1 (0.65) | LPLLIPGTRPV1MGLLCA1 | |
| SCHEMBL7610345 | 0.91 | NR5A1 (0.65) | LPLLIPGTRPV1MGLLCA1 | |
| SCHEMBL8705732 | 0.91 | NR5A1 (0.65) | LPLLIPGTRPV1MGLLCA1 | |
| SCHEMBL2401172 | 0.91 | NR5A1 (0.65) | LPLLIPGTRPV1MGLLCA1 | |
| SCHEMBL7472946 | 0.91 | NR5A1 (0.65) | LPLLIPGTRPV1MGLLCA1 | |
| SCHEMBL2354047 | 0.91 | NR5A1 (0.65) | LPLLIPGTRPV1MGLLCA1 | |
| SCHEMBL2671160 | 0.91 | NR5A1 (0.65) | LPLLIPGTRPV1MGLLCA1 | |
| SCHEMBL8216263 | 0.91 | NR5A1 (0.65) | LPLLIPGTRPV1MGLLCA1 | |
| SCHEMBL8208913 | 0.91 | NR5A1 (0.65) | LPLLIPGTRPV1MGLLCA1 | |
| SCHEMBL1006706 | 0.89 | NR5A1 (0.61) | LPLLIPGTRPV1MGLLCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102652-B2 | Dichroic-photochromic 2H-naphtho[1,2-b]pyran compounds and devices | ALPHAMICRON INCORPORATED (US) | 2015-08-11 | — | — | US | disclosed |
| EP-2076504-B1 | DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES | ALPHAMICRON INC (US) | 2014-05-14 | — | — | EP | disclosed |
| US-8697890-B2 | Dichroic-photochromic 2H-naphtho[1,2-b]pyran compounds and devices | ALPHAMICRON INCORPORATED (US) | 2014-04-15 | — | — | US | disclosed |
| US-20100324296-A1 | DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES | ALPHAMICRON INCORPORATED | 2010-12-23 | — | — | US | disclosed |
| EP-2076504-A2 | DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES | AlphaMicron, Inc. (US) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008051420-A2 | DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES | ALPHAMICRON, INC. (US) | 2008-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324296-A1 | DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES | NR0B2, NR0B1, NR2E3 | LPL 4371/4885LIPG 4715/4885TRPV1 484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.