Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3779586 | 0.94 | KDM1A (0.37) | KDM1AMAOBAKT1MAP4K4MINK1 | |
| SCHEMBL3770731 | 0.90 | SLC22A12 (0.38) | EGLN1SLC22A12CTSA | |
| SCHEMBL3776531 | 0.88 | MAP4K4 (0.37) | MAP4K4MINK1KCNH2CTSA | |
| SCHEMBL3772521 | 0.88 | ABL1 (0.38) | MAP4K4SLC22A12 | |
| SCHEMBL3780251 | 0.86 | XDH (0.46) | KDM1AAKT1MAP4K4MINK1TNIK | |
| SCHEMBL3768528 | 0.84 | SLC22A12 (0.37) | EGLN1SLC22A12CTSA | |
| SCHEMBL3781398 | 0.83 | FFAR4 (0.35) | — | |
| SCHEMBL3780099 | 0.83 | MAP4K4 (0.36) | MAP4K4MINK1KCNH2CTSA | |
| SCHEMBL3770701 | 0.82 | ABL1 (0.36) | CTSA | |
| SCHEMBL3779564 | 0.81 | ROCK1 (0.33) | AKT1MAP4K4MINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317698-A1 | Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxyalkylene-Cyclopropanamine Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them | LES LABORATOIRES SERVIER (FR) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317698-A1 | Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxyalkylene-Cyclopropanamine Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them | CHRNA6, CHRNE, CHRNG | KDM1A 1957/4885MAOB 674/4885AKT1 1820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.