Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3775172 | 0.93 | ALDH1A1 (0.45) | ALDH1A1HSD17B10CYP1B1HIF1AHPRT1 | |
| SCHEMBL2274784 | 0.87 | ESR1 (0.50) | ALDH1A1ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL3785955 | 0.87 | CYP11B1 (0.41) | ALDH1A1HSD17B10CYP1B1HIF1AHPRT1 | |
| SCHEMBL11898490 | 0.84 | ESR1 (0.47) | ALDH1A1HSD17B10HIF1ATDP1ESR1 | |
| SCHEMBL3777200 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP1B1HIF1AHPRT1 | |
| SCHEMBL2271000 | 0.83 | ESR1 (0.50) | ALDH1A1ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL2267781 | 0.83 | MCL1 (0.43) | HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL18317630 | 0.83 | ESR1 (0.44) | ALDH1A1HSD17B10CYP1B1HIF1AESR1 | |
| SCHEMBL3783466 | 0.83 | ALDH1A1 (0.45) | ALDH1A1HSD17B10CYP1B1HIF1AHPRT1 | |
| SCHEMBL394160 | 0.82 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CYP1B1HIF1AHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8568903-B2 | Phenanthrene derivative, and material for organic EL element | IDEMITSU KOSAN CO., LTD. (JP) | 2013-10-29 | — | — | US | disclosed |
| US-20100327230-A1 | PHENANTHRENE DERIVATIVE, AND MATERIAL FOR ORGANIC EL ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100327230-A1 | PHENANTHRENE DERIVATIVE, AND MATERIAL FOR ORGANIC EL ELEMENT | LEF1, AR, NR0B1 | ALDH1A1 1250/4885HSD17B10 2313/4885CYP1B1 505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.