Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 6/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3778270 | 0.88 | HPGD (0.37) | HPGDF10L3MBTL1SLC6A4HRH3 | |
| SCHEMBL3778272 | 0.88 | HPGD (0.37) | HPGDF10L3MBTL1SLC6A4HRH3 | |
| SCHEMBL3778740 | 0.87 | HPGD (0.37) | HPGDL3MBTL1HSD17B10NPY4R | |
| SCHEMBL3782626 | 0.87 | TDP1 (0.38) | HPGDL3MBTL1HSD17B10 | |
| SCHEMBL3778409 | 0.86 | ALDH1A1 (0.39) | HPGDL3MBTL1SLC6A4HSD17B10 | |
| SCHEMBL3781667 | 0.86 | F10 (0.39) | F10 | |
| SCHEMBL3775253 | 0.83 | PTGDR (0.38) | HPGDL3MBTL1 | |
| SCHEMBL3777868 | 0.83 | TSHR (0.39) | HPGDL3MBTL1 | |
| SCHEMBL3776986 | 0.83 | HPGD (0.41) | HPGDL3MBTL1HSD17B10NPY4R | |
| SCHEMBL3778224 | 0.80 | ALDH1A1 (0.37) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928457-B1 | QUINOLINES AND THEIR THERAPEUTIC USE | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2012-12-12 | — | — | EP | disclosed |
| US-7858640-B2 | Quinolines and their therapeutic use | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-28 | — | — | US | disclosed |
| US-20090156600-A1 | Quinolines and Their Therapeutic Use | GB005, INC. | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156600-A1 | Quinolines and Their Therapeutic Use | NR3C1, NR3C2, NR1H3 | HPGD 1772/4885F10 1999/4885L3MBTL1 3442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.