Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28299441 | 0.86 | — | — | |
| SCHEMBL16635550 | 0.82 | — | — | |
| SCHEMBL1412413 | 0.79 | NPSR1 (0.42) | KMT2A | |
| SCHEMBL2186183 | 0.78 | ALDH1A1 (0.35) | — | |
| SCHEMBL16856775 | 0.68 | HCAR2 (0.36) | MEN1KMT2A | |
| SCHEMBL18838974 | 0.68 | MCL1 (0.31) | — | |
| SCHEMBL17627086 | 0.68 | ALDH1A1 (0.35) | MEN1KMT2A | |
| SCHEMBL936108 | 0.68 | GLA (0.37) | MEN1KMT2A | |
| SCHEMBL8915968 | 0.67 | — | — | |
| SCHEMBL27605193 | 0.67 | SRC (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258690-B1 | Tricyclic amines as intermediates in the synthesis of fungicidal carboxamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-20 | — | — | EP | disclosed |
| EP-2258690-A1 | Tricyclic amines as intermediates in the synthesis of fungicidal carboxamide derivatives | Syngenta Participations AG (CH) | 2010-12-08 | — | — | EP | disclosed |
| US-20090216027-A1 | MICROBIOCIDAL (E.G. FUNGICIDAL) 1,2,3-TRIAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| US-7531559-B2 | Fungicidal 1,2,3 triazole derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2009-05-12 | — | — | US | disclosed |
| US-20060154967-A1 | e.g. [2-methyl-5-trifluoromethyl-2H-1,2,3-triazole-4-carboxylic acid methyl ester; fungicide; against the phytopathogenic fungi: Fungi imperfecti (Botrytis, Pyricularia, Helminthosporium), Basidiomycetes (Rhizoctonia, Hemileia), Ascomycetes classes (Venturia, Erysiphe), Oomycetes classes (Phytophthora) | SYNGENTA CROP PROTECTION, INC. | 2006-07-13 | — | — | US | disclosed |
| EP-1539717-A2 | MICROBIOCIDAL (E.G FUNGICIDAL) 1,2,3-TRIAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018438-A2 | MICROBIOCIDAL (E.G. FUNGICIDAL) 1,2,3-TRIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154967-A1 | e.g. [2-methyl-5-trifluoromethyl-2H-1,2,3-triazole-4-carboxylic acid methyl ester; fungicide; against the phytopathogenic fungi: Fungi imperfecti (Botrytis, Pyricularia, Helminthosporium), Basidiomycetes (Rhizoctonia, Hemileia), Ascomycetes classes (Venturia, Erysiphe), Oomycetes classes (Phytophthora) | CBR3, PAH, CBR1 | MEN1 1691/4885KMT2A 1907/4885 |
| US-20090216027-A1 | MICROBIOCIDAL (E.G. FUNGICIDAL) 1,2,3-TRIAZOLE DERIVATIVES | CBR3, CCR4, CBR1 | MEN1 1061/4885KMT2A 3927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.