Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL11036897 | 1.00 | CA2 (0.50) | CA2SLC34A1FDPSBLMTDP1 | |
| Phosphoric Acid SCHEMBL11651209 | 1.00 | CA2 (0.50) | CA2SLC34A1FDPSBLMTDP1 | |
| Phosphoric Acid SCHEMBL5449618 | 1.00 | CA2 (0.50) | CA2SLC34A1FDPSBLMTDP1 | |
| Phosphoric Acid SCHEMBL8852334 | 1.00 | CA2 (0.50) | CA2SLC34A1FDPSBLMTDP1 | |
| Phosphoric Acid SCHEMBL22117087 | 1.00 | CA2 (0.50) | CA2SLC34A1FDPSBLMTDP1 | |
| Phosphoric Acid SCHEMBL9701339 | 1.00 | CA2 (0.50) | CA2SLC34A1FDPSBLMTDP1 | |
| Phosphoric Acid SCHEMBL298140 | 1.00 | CA2 (0.50) | CA2SLC34A1FDPSBLMTDP1 | |
| Phosphoric Acid SCHEMBL1018169 | 1.00 | — | — | |
| Phosphoric Acid SCHEMBL21569209 | 1.00 | CA2 (0.50) | CA2SLC34A1FDPSBLMTDP1 | |
| Phosphoric Acid SCHEMBL10585058 | 1.00 | CA2 (0.50) | CA2SLC34A1FDPSBLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167606-A | For treating the implantation material and external member of bone defect | 艾斯丘莱普股份公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-107635544-A | Individual layer tooth whitening system | 皇家飞利浦有限公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-101522051-B | Cooling confectioneries and beverage | INTERCONTINENTAL GREAT BRANDS LLC (US) | 2016-01-13 | — | — | CN | disclosed |
| CN-103232233-B | Porous nano-ceramic constructed by hydroxyapatite nanorods or sheets and preparation method thereof | UNIV SICHUAN | 2014-12-17 | — | — | CN | disclosed |
| CN-103232233-A | Porous nano-ceramic constructed by hydroxyapatite nanorods or sheets and preparation method thereof | UNIV SICHUAN | 2013-08-07 | — | — | CN | disclosed |
| US-7857860-B2 | Bone void filler and method of manufacture | THERICS, LLC (US) | 2010-12-28 | — | — | US | disclosed |
| CN-101522051-A | Cooling confectioneries and beverages | CADBURY ADAMS USA LLC (US) | 2009-09-02 | — | — | CN | disclosed |
| EP-1983835-A2 | ANTIMICROBIAL MATERIALS | Smith & Nephew, PLC (GB) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007085852-A2 | ANTIMICROBIAL MATERIALS | SMITH & NEPHEW, PLC (GB) | 2007-08-02 | — | — | WO | disclosed |
| US-20050177237-A1 | Spinal cage insert, filler piece and method of manufacturing | AFBS, INC. | 2005-08-11 | — | — | US | disclosed |
| US-20050085922-A1 | Shaped filler for implantation into a bone void and methods of manufacture and use thereof | THERICS, LLC | 2005-04-21 | — | — | US | disclosed |