Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.55 |
| ▸ | CHRNA10 | Q9GZZ6 | 3/20 | 0.55 |
| ▸ | CHRNA9 | Q9UGM1 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788680 | 0.88 | KMT2A (0.60) | KMT2ACHRNA7CHRNA10CHRNA9RAB9A | |
| SCHEMBL3789573 | 0.87 | KMT2A (0.61) | KMT2ACHRNA7CHRNA10CHRNA9NPC1 | |
| SCHEMBL3809249 | 0.84 | KMT2A (0.56) | KMT2ACHRNA7CHRNA10CHRNA9NPC1 | |
| SCHEMBL16339023 | 0.80 | DYRK1A (0.43) | KMT2ARAB9APOLB | |
| SCHEMBL3782560 | 0.79 | KMT2A (0.55) | KMT2ACHRNA7CHRNA10CHRNA9NPC1 | |
| SCHEMBL25725737 | 0.78 | PARP1 (0.51) | KMT2ANPC1RAB9ALMNATP53 | |
| SCHEMBL25725661 | 0.76 | KDM4E (0.50) | KMT2ANPC1RAB9ALMNAMAPT | |
| SCHEMBL9376961 | 0.75 | ALDH1A1 (0.53) | KMT2ANPC1RAB9ALMNATP53 | |
| SCHEMBL13036340 | 0.75 | PPARG (0.54) | KMT2ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL1744256 | 0.75 | ZAP70 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143803-A2 | NEW NICOTINAMIDE DERIVATIVES WITH ANTI-ANDROGEN EFFECTS, PROCESSES OF PREPARING, AND ANTIANDROGENS COMPRISING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2010-12-16 | — | — | WO | claimed |
| WO-2010143803-A2 | NEW NICOTINAMIDE DERIVATIVES WITH ANTI-ANDROGEN EFFECTS, PROCESSES OF PREPARING, AND ANTIANDROGENS COMPRISING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2010-12-16 | — | — | WO | disclosed |