Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.56 |
| ▸ | CHRNA10 | Q9GZZ6 | 3/20 | 0.56 |
| ▸ | CHRNA9 | Q9UGM1 | 3/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809249 | 0.90 | KMT2A (0.56) | KMT2ANPC1RAB9AMAPTLMNA | |
| SCHEMBL3788680 | 0.90 | KMT2A (0.60) | KMT2ARAB9ASMN1; SMN2L3MBTL1CHRNA7 | |
| SCHEMBL3782446 | 0.87 | KMT2A (0.57) | KMT2ANPC1RAB9AMAPTLMNA | |
| SCHEMBL3782560 | 0.83 | KMT2A (0.55) | KMT2ANPC1RAB9ACHRNA7CHRNA10 | |
| SCHEMBL2865126 | 0.81 | RAB9A (0.60) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3785591 | 0.78 | MAP3K5 (0.51) | KMT2ACHRNA7CHRNA10CHRNA9GRM5 | |
| SCHEMBL27696834 | 0.78 | MCHR1 (0.60) | KMT2ANPC1RAB9AMAPTLMNA | |
| SCHEMBL13296220 | 0.76 | GRM5 (0.82) | KMT2ANPC1RAB9AMAPTLMNA | |
| SCHEMBL3787990 | 0.76 | KMT2A (1.00) | KMT2ANPC1RAB9AMAPTLMNA | |
| SCHEMBL30175325 | 0.76 | UBE2T (0.56) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143803-A2 | NEW NICOTINAMIDE DERIVATIVES WITH ANTI-ANDROGEN EFFECTS, PROCESSES OF PREPARING, AND ANTIANDROGENS COMPRISING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2010-12-16 | — | — | WO | claimed |
| WO-2010143803-A2 | NEW NICOTINAMIDE DERIVATIVES WITH ANTI-ANDROGEN EFFECTS, PROCESSES OF PREPARING, AND ANTIANDROGENS COMPRISING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010143803-A2 | NEW NICOTINAMIDE DERIVATIVES WITH ANTI-ANDROGEN EFFECTS, PROCESSES OF PREPARING, AND ANTIANDROGENS COMPRISING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2010-12-16 | — | — | WO | disclosed |