Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3190628 | 0.75 | MEN1 (0.56) | KMT2AALDH1A1MEN1HTTNPC1 | |
| SCHEMBL14960416 | 0.75 | KMT2A (0.59) | KMT2AALDH1A1MEN1APEX1LCK | |
| SCHEMBL13015630 | 0.73 | KMT2A (0.58) | KMT2AALDH1A1MEN1HTTAPEX1 | |
| SCHEMBL3188023 | 0.73 | ATAD2 (0.51) | KMT2AALDH1A1MEN1HTTTSHR | |
| SCHEMBL3197114 | 0.73 | CCNE1 (0.41) | KMT2ASMN1; SMN2 | |
| SCHEMBL7278026 | 0.72 | MAPT (0.50) | ALDH1A1NPC1GAARAB9ASMN1; SMN2 | |
| SCHEMBL2753548 | 0.70 | RAB9A (0.57) | KMT2AALDH1A1MEN1LCKNPC1 | |
| SCHEMBL11420377 | 0.69 | GCK (0.46) | KMT2AALDH1A1MEN1HTTTSHR | |
| SCHEMBL3766107 | 0.69 | NPC1 (0.70) | KMT2AALDH1A1MEN1HTTNPC1 | |
| SCHEMBL9074005 | 0.69 | GCK (0.35) | KMT2AALDH1A1MEN1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298385-A1 | PROTEIN KINASE INHIBITORS USEFUL FOR TREATMENT OF CANCERS | DU, XIAOMIN (CN) | 2010-11-25 | — | — | US | disclosed |
| US-20100298385-A1 | PROTEIN KINASE INHIBITORS USEFUL FOR TREATMENT OF CANCERS | DU, XIAOMIN (CN) | 2010-11-25 | — | — | US | disclosed |
| US-20100298385-A1 | PROTEIN KINASE INHIBITORS USEFUL FOR TREATMENT OF CANCERS | DU, XIAOMIN (CN) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298385-A1 | PROTEIN KINASE INHIBITORS USEFUL FOR TREATMENT OF CANCERS | MAP3K6, MAP3K20, MAP3K5 | KMT2A 1064/4885ALDH1A1 3089/4885MEN1 1690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.