Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | NMT1 | P30419 | 8/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3792388 | 0.78 | SLC6A2 (0.48) | HRH1 | |
| SCHEMBL3714344 | 0.78 | SLC6A2 (0.44) | HRH1 | |
| SCHEMBL3786278 | 0.77 | HRH1 (0.53) | HRH1NMT1 | |
| SCHEMBL30735992 | 0.74 | MAPT (0.48) | HRH1 | |
| SCHEMBL19297264 | 0.74 | MAPT (0.48) | HRH1 | |
| SCHEMBL3790744 | 0.72 | HRH1 (0.48) | HRH1 | |
| Hydrochloric Acid SCHEMBL23360094 | 0.72 | IRAK1 (0.45) | HRH1 | |
| SCHEMBL3715640 | 0.72 | DDB1 (0.53) | HRH1 | |
| SCHEMBL3791590 | 0.70 | HTR1A (0.45) | HRH1 | |
| Hydrochloric Acid SCHEMBL23360018 | 0.70 | SLC40A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |