Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.58 |
| ▸ | SMO | Q99835 | 12/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1360932 | 0.85 | SMO (0.61) | NR3C1SMOPGR | |
| SCHEMBL5135413 | 0.82 | CYP11B2 (0.71) | NR3C1PGR | |
| SCHEMBL4853828 | 0.80 | SMO (0.59) | NR3C1SMOPGR | |
| SCHEMBL29573526 | 0.80 | NR3C1 (0.62) | NR3C1SMOPGR | |
| SCHEMBL1361065 | 0.80 | NR3C1 (0.62) | NR3C1SMOPGR | |
| SCHEMBL28782071 | 0.79 | NR3C1 (0.42) | NR3C1SMOPGR | |
| SCHEMBL22225746 | 0.78 | NR3C1 (0.74) | NR3C1PGR | |
| SCHEMBL443024 | 0.77 | NR3C1 (0.62) | NR3C1SMOPGR | |
| SCHEMBL413100 | 0.77 | NR3C1 (0.62) | NR3C1SMOPGR | |
| SCHEMBL3011613 | 0.77 | NR3C1 (0.62) | NR3C1SMOPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010082044-A1 | UNSATURATED BICYCLIC HETEROCYCLIC DERIVATIVES AS SMO ANTAGONISTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2010-07-22 | — | — | WO | disclosed |