Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355182 | 0.86 | TSHR (0.57) | POLBCYP1A2TSHRALDH1A1RAB9A | |
| SCHEMBL10576835 | 0.85 | TSHR (0.54) | POLBCYP1A2TSHRALDH1A1RAB9A | |
| SCHEMBL10572891 | 0.82 | TSHR (0.47) | POLBCYP1A2TSHRALDH1A1CYP19A1 | |
| SCHEMBL10576911 | 0.81 | KCNA5 (0.49) | CYP1A2TSHRALDH1A1RAB9ANPC1 | |
| SCHEMBL3912124 | 0.79 | ALDH1A1 (0.40) | POLBCYP1A2TSHRALDH1A1RAB9A | |
| SCHEMBL3916139 | 0.79 | CYP1A2 (0.40) | POLBCYP1A2TSHRALDH1A1RAB9A | |
| Methyl Alcohol SCHEMBL3396777 | 0.79 | ALDH1A1 (0.53) | POLBCYP1A2TSHRALDH1A1RAB9A | |
| SCHEMBL22891107 | 0.78 | POLB (0.60) | POLBCYP1A2TSHRALDH1A1RAB9A | |
| SCHEMBL3909811 | 0.78 | CYP1A2 (0.41) | POLBCYP1A2TSHRALDH1A1RAB9A | |
| SCHEMBL3912979 | 0.78 | POLB (0.39) | POLBCYP1A2TSHRALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858376-B2 | Ninhydrin and ionic liquid reagent mixture and method for the visualization of amino acids and peptides | MERCK PATENT GESELLSCHAFT (DE) | 2010-12-28 | — | — | US | disclosed |
| US-20090258427-A1 | Method and Reagent Mixture for the Visualization of Amino Acids and Peptides | MERCK PATENT GMBH (DE) | 2009-10-15 | — | — | US | disclosed |
| US-4877795-A | 4H-quinolizin-4-one compounds useful for the treatment of allergic bronchial asthma, allergic rhinitis atropic dermatitis and the like | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258427-A1 | Method and Reagent Mixture for the Visualization of Amino Acids and Peptides | VIP, NEFM, NGLY1 | POLB 4045/4885CYP1A2 4877/4885TSHR 3002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.