SCHEMBL3912979

SCHEMBL3912979

CCO[SiH](OCC)C(CC)OC(=O)Cc1ccccn1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.39
ALDH1A1 P00352 3/20 0.39
CYP1A2 P05177 1/20 0.39
TSHR P16473 1/20 0.39
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
PTPRA P18433 1/20 0.38
KDM4E B2RXH2 3/20 0.37
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
HIF1A Q16665 1/20 0.36
TRPM8 Q7Z2W7 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3912985 0.90 ALDH1A1 (0.37) POLBALDH1A1CYP1A2TSHRRAB9A
SCHEMBL3916139 0.88 CYP1A2 (0.40) POLBALDH1A1CYP1A2TSHRRAB9A
SCHEMBL3912124 0.86 ALDH1A1 (0.40) POLBALDH1A1CYP1A2TSHRRAB9A
SCHEMBL3911723 0.79 PKM (0.45) POLBALDH1A1RAB9ANPC1KDM4E
SCHEMBL3912984 0.79 PGR (0.39) POLBALDH1A1CYP1A2TSHRRAB9A
SCHEMBL3919101 0.79 ALDH1A1 (0.38) POLBALDH1A1CYP1A2TSHRRAB9A
SCHEMBL3783374 0.78 POLB (0.47) POLBALDH1A1CYP1A2TSHRRAB9A
SCHEMBL3914952 0.77 CYP19A1 (0.40) POLBALDH1A1CYP1A2TSHRRAB9A
SCHEMBL355182 0.76 TSHR (0.57) POLBALDH1A1CYP1A2TSHRRAB9A
SCHEMBL3909811 0.75 CYP1A2 (0.41) POLBALDH1A1CYP1A2TSHRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed