Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165352 | 0.93 | TSHR (0.55) | TSHRKCNJ1LOXL2IDO1KCNH2 | |
| SCHEMBL8727026 | 0.93 | TSHR (0.55) | TSHRKCNJ1LOXL2IDO1KCNH2 | |
| SCHEMBL11308396 | 0.93 | TSHR (0.55) | TSHRKCNJ1LOXL2IDO1KCNH2 | |
| SCHEMBL5631593 | 0.90 | TSHR (0.49) | TSHRKCNJ1LOXL2IDO1KCNH2 | |
| SCHEMBL3656180 | 0.88 | TSHR (0.62) | TSHRKCNJ1LOXL2IDO1KCNH2 | |
| SCHEMBL18913824 | 0.86 | TSHR (0.69) | TSHRKCNJ1LOXL2IDO1KCNH2 | |
| SCHEMBL30758863 | 0.86 | TSHR (0.69) | TSHRKCNJ1LOXL2IDO1KCNH2 | |
| SCHEMBL19929796 | 0.85 | KCNH2 (0.66) | TSHRKCNJ1KCNH2EPHX1 | |
| SCHEMBL1310286 | 0.85 | KCNH2 (0.51) | TSHRKCNJ1LOXL2IDO1KCNH2 | |
| SCHEMBL6696078 | 0.84 | KCNH2 (0.54) | TSHRKCNJ1LOXL2IDO1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408741-A1 | METHOD FOR COUPLING HALOGEN-SUBSTITUTED AROMATIC COMPOUNDS WITH ORGANIC COMPOUNDS COMPRISING TRIALKYLSILYL-SUBSTITUTED HETEROATOMS | Zylum Beteiligungsgesellschaft mbH & Co. Patente II KG (DE) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010106078-A1 | METHOD FOR COUPLING HALOGEN-SUBSTITUTED AROMATIC COMPOUNDS WITH ORGANIC COMPOUNDS COMPRISING TRIALKYLSILYL-SUBSTITUTED HETEROATOMS | ZYLUM BETEILIGUNGSGESELLSCHAFT MBH & CO. PATENTE II KG (DE) | 2010-09-23 | — | — | WO | disclosed |