Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KMT5B | Q4FZB7 | 1/20 | 0.41 |
| ▸ | KMT5C | Q86Y97 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31720600 | 1.00 | KDM4E (0.59) | KDM4EGAAMAPTSMN1; SMN2TSHR | |
| SCHEMBL20338435 | 0.91 | KDM4E (0.46) | KDM4EGAAMAPTSMN1; SMN2TSHR | |
| SCHEMBL26861418 | 0.83 | OPRL1 (0.42) | KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL5089851 | 0.82 | KDM4E (0.53) | KDM4EGAAMAPTSMN1; SMN2TSHR | |
| SCHEMBL5046395 | 0.82 | KDM4E (0.61) | KDM4EGAAMAPTSMN1; SMN2TSHR | |
| SCHEMBL26861434 | 0.81 | POLB (0.50) | KDM4EGAAMAPTPOLBALDH1A1 | |
| SCHEMBL3791325 | 0.81 | KDM4E (0.51) | KDM4EGAAMAPTSMN1; SMN2TSHR | |
| SCHEMBL3787465 | 0.80 | KDM4E (0.58) | KDM4EGAAMAPTSMN1; SMN2TSHR | |
| SCHEMBL19403829 | 0.80 | KDM4E (0.58) | KDM4EGAAMAPTSMN1; SMN2TSHR | |
| SCHEMBL30936608 | 0.79 | KDM4E (0.59) | KDM4EGAAMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | KDM4E 2606/4885GAA 1755/4885MAPT 3312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.