SCHEMBL3784500

SCHEMBL3784500

C=C(C)C(=O)OCCCOc1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
TDP1 Q9NUW8 4/20 0.46
POLB P06746 1/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
KDM4E B2RXH2 2/20 0.43
THRB P10828 1/20 0.40
AHR P35869 1/20 0.39
PLAU P00749 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 4/20 0.38
ABCB1 P08183 1/20 0.38
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
S1PR4 O95977 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6900262 0.92 THRB (0.45) TSHRTDP1POLBAPEX1HTT
SCHEMBL11175016 0.86 TDP1 (0.42) TSHRTDP1POLBAPEX1HTT
SCHEMBL11185791 0.86 POLB (0.42) TSHRTDP1POLBAPEX1HTT
SCHEMBL3780952 0.81 MAPT (0.57) TSHRTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL11170985 0.81 THRB (0.42) TSHRTDP1POLBAPEX1HTT
SCHEMBL11172667 0.81 THRB (0.42) TSHRTDP1POLBAPEX1HTT
SCHEMBL11812323 0.80 TSHR (0.54) TSHRTDP1POLBAPEX1HTT
SCHEMBL10604787 0.79 TSHR (0.46) TSHRTDP1POLBAPEX1HTT
SCHEMBL8957604 0.78 THRB (0.41) TSHRTDP1POLBAPEX1HTT
SCHEMBL11181664 0.78 THRB (0.41) TSHRTDP1POLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1917236-B1 CHROMOPHORIC POLYMER MEMPILE INC (US) 2010-08-18 EP claimed
US-20080197322-A1 ADDITIVES AND COMONOMERS FOR THE ENHANCEMENT OF POLYMER PROPERTIES MEMPILE INC. (US) 2008-08-21 US claimed
EP-1917236-A1 CHROMOPHORIC POLYMER Mempile Inc. (US) 2008-05-07 EP claimed
WO-2007010519-A1 CHROMOPHORIC POLYMER MEMPILE INC. (US) 2007-01-25 WO claimed
US-20100290332-A1 OPTICAL DATA CARRIER WITH REFERENCE LAYER MEMPILE INC. (US) 2010-11-18 US disclosed
US-20100290332-A1 OPTICAL DATA CARRIER WITH REFERENCE LAYER MEMPILE INC. (US) 2010-11-18 US disclosed
EP-1917236-B1 CHROMOPHORIC POLYMER MEMPILE INC (US) 2010-08-18 EP disclosed
US-20100119761-A1 OPTICAL 3D MEMORY COMPRISING A BLOCK COPOLYMER CONTAINING A PHOTOACTIVE MONOMER HAVING A PHOTOISOMERABLE GROUP ARKEMA FRANCE (FR) 2010-05-13 US disclosed
US-20080291810-A1 Multi-Layer Three Dimensional Non-Linear Optical Data Carrier and Method of Recording/Reading Data Therein MEMPILE INC. C/O PHS CORPORATE SERVICES, INC. (US) 2008-11-27 US disclosed
WO-2008139453-A2 OPTICAL DATA CARRIER WITH REFERENCE LAYER MEMPILE INC. (US) 2008-11-20 WO disclosed
US-20080197322-A1 ADDITIVES AND COMONOMERS FOR THE ENHANCEMENT OF POLYMER PROPERTIES MEMPILE INC. (US) 2008-08-21 US disclosed
US-20080197322-A1 ADDITIVES AND COMONOMERS FOR THE ENHANCEMENT OF POLYMER PROPERTIES MEMPILE INC. (US) 2008-08-21 US disclosed
US-20080197322-A1 ADDITIVES AND COMONOMERS FOR THE ENHANCEMENT OF POLYMER PROPERTIES MEMPILE INC. (US) 2008-08-21 US disclosed
EP-1955324-A2 MULTI-LAYER THREE DIMENSIONAL NON-LINEAR OPTICAL DATA CARRIER AND METHOD OF RECORDING/READING DATA THEREIN Mempile Inc. (US) 2008-08-13 EP disclosed
EP-1917236-A1 CHROMOPHORIC POLYMER Mempile Inc. (US) 2008-05-07 EP disclosed
WO-2007060674-A2 MULTI-LAYER THREE DIMENSIONAL NON-LINEAR OPTICAL DATA CARRIER AND METHOD OF RECORDING/READING DATA THEREIN MEMPILE INC. (US) 2007-05-31 WO disclosed
WO-2007010519-A1 CHROMOPHORIC POLYMER MEMPILE INC. (US) 2007-01-25 WO disclosed
WO-2007010519-A1 CHROMOPHORIC POLYMER MEMPILE INC. (US) 2007-01-25 WO disclosed