Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3784500 | 0.92 | TSHR (0.46) | THRBTDP1KDM4EMAPTHTT | |
| SCHEMBL11172667 | 0.88 | THRB (0.42) | THRBTDP1KDM4EMAPTHTT | |
| SCHEMBL11170985 | 0.88 | THRB (0.42) | THRBTDP1KDM4EMAPTHTT | |
| SCHEMBL11181664 | 0.85 | THRB (0.41) | THRBTDP1KDM4EMAPTHTT | |
| SCHEMBL8957604 | 0.85 | THRB (0.41) | THRBTDP1KDM4EMAPTHTT | |
| SCHEMBL9880805 | 0.80 | MAPT (0.41) | THRBTDP1KDM4EMAPTHTT | |
| SCHEMBL11143904 | 0.80 | THRB (0.50) | THRBTDP1HTTPOLBAPEX1 | |
| SCHEMBL11658731 | 0.80 | TSHR (0.46) | KDM4EMAPTPOLBTSHRABCB1 | |
| SCHEMBL11185791 | 0.79 | POLB (0.42) | THRBTDP1KDM4EMAPTHTT | |
| SCHEMBL11175016 | 0.79 | TDP1 (0.42) | THRBTDP1KDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1225603-A | — | — | None | — | — | JP | disclosed |
| JP-2004315458-A | METHOD FOR REFINING EPISULFIDE COMPOSITION | MITSUI CHEMICALS INC | 2004-11-11 | — | — | JP | disclosed |
| JP-H01225603-A | RESIN MATERIAL HAVING HIGH REFRACTIVE INDEX | KUREHA CHEM IND CO LTD | 1989-09-08 | — | — | JP | disclosed |
| US-4812032-A | DIBROMOSTYRENE, DIVINYLBENZENE, HALOGEN CONTAINING ACRYLATE OR METHACRYLATE | TORAY INDUSTRIES, INC. (JP) | 1989-03-14 | — | — | US | disclosed |
| US-4721377-A | COPOLYMER OF DIBROMOSTYRENE, DI-(OR TRI-) (METH-)ACRYLATE AND MONO (METH-)ACRYLATE | TORAY INDUSTRIES, INC. (JP) | 1988-01-26 | — | — | US | disclosed |
| EP-0176874-A2 | A highly-refractive plastic lens | TORAY INDUSTRIES, INC. (JP) | 1986-04-09 | — | — | EP | disclosed |