Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897835 | 0.86 | NPC1 (0.52) | NPC1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL4632930 | 0.78 | NPC1 (0.59) | NPC1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL5218836 | 0.76 | NPC1 (0.58) | NPC1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL3707478 | 0.75 | NPC1 (0.57) | NPC1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7884074 | 0.74 | NPC1 (0.47) | NPC1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL10487703 | 0.74 | KMT2A (0.52) | NPC1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL10487679 | 0.73 | ALDH1A1 (0.51) | NPC1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7929808 | 0.73 | CA12 (0.50) | NPC1ALDH1A1MAPTRAB9AESR1 | |
| SCHEMBL6815909 | 0.73 | KMT2A (0.59) | NPC1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL450492 | 0.72 | NPC1 (0.59) | NPC1KMT2AALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |